{"id":4222,"date":"2026-02-22T22:11:26","date_gmt":"2026-02-22T19:11:26","guid":{"rendered":"https:\/\/alnajmi.net\/portal\/?p=4222"},"modified":"2026-02-23T19:06:49","modified_gmt":"2026-02-23T16:06:49","slug":"%d8%a3%d9%81%d8%b6%d9%84-%d8%ad%d8%a8%d9%88%d8%a8-%d9%84%d9%84%d8%a7%d9%86%d8%aa%d8%b5%d8%a7%d8%a8-%d8%af%d9%84%d9%8a%d9%84-%d8%b7%d8%a8%d9%8a-%d8%a2%d9%85%d9%86-%d9%88%d9%88%d8%a7%d9%82%d8%b9%d9%8a","status":"publish","type":"post","link":"https:\/\/alnajmi.net\/portal\/%d8%a3%d9%81%d8%b6%d9%84-%d8%ad%d8%a8%d9%88%d8%a8-%d9%84%d9%84%d8%a7%d9%86%d8%aa%d8%b5%d8%a7%d8%a8-%d8%af%d9%84%d9%8a%d9%84-%d8%b7%d8%a8%d9%8a-%d8%a2%d9%85%d9%86-%d9%88%d9%88%d8%a7%d9%82%d8%b9%d9%8a\/","title":{"rendered":"\u0623\u0641\u0636\u0644 \u062d\u0628\u0648\u0628 \u0644\u0644\u0627\u0646\u062a\u0635\u0627\u0628: \u062f\u0644\u064a\u0644 \u0637\u0628\u064a \u0622\u0645\u0646 \u0648\u0648\u0627\u0642\u0639\u064a"},"content":{"rendered":"

\u0623\u0641\u0636\u0644 \u062d\u0628\u0648\u0628 \u0644\u0644\u0627\u0646\u062a\u0635\u0627\u0628: \u0645\u0627\u0630\u0627 \u064a\u0639\u0646\u064a \u201c\u0627\u0644\u0623\u0641\u0636\u0644\u201d \u0637\u0628\u064a\u064b\u0627\u061f<\/h1>\n

\u0639\u0646\u062f\u0645\u0627 \u064a\u0643\u062a\u0628 \u0627\u0644\u0646\u0627\u0633 \u0641\u064a \u0645\u062d\u0631\u0643\u0627\u062a \u0627\u0644\u0628\u062d\u062b \u0639\u0628\u0627\u0631\u0629 Best pills for<\/a> erection<\/strong> \u0641\u0647\u0645 \u063a\u0627\u0644\u0628\u064b\u0627 \u0644\u0627 \u064a\u0628\u062d\u062b\u0648\u0646 \u0639\u0646 \u201c\u062d\u0628\u0651\u0629 \u0633\u062d\u0631\u064a\u0629\u201d\u060c \u0628\u0644 \u0639\u0646 \u062d\u0644\u0651 \u0639\u0645\u0644\u064a \u0644\u0645\u0634\u0643\u0644\u0629 \u062a\u0645\u0633\u0651 \u0627\u0644\u062b\u0642\u0629 \u0628\u0627\u0644\u0646\u0641\u0633 \u0648\u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0648\u062c\u0648\u062f\u0629 \u0627\u0644\u062d\u064a\u0627\u0629. \u0648\u0647\u0630\u0627 \u0645\u0641\u0647\u0648\u0645 \u062a\u0645\u0627\u0645\u064b\u0627. \u0639\u0644\u0649 \u0645\u062f\u0627\u0631 \u0633\u0646\u0648\u0627\u062a \u0639\u0645\u0644\u064a \u0641\u064a \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0637\u0628\u064a \u0648\u0645\u0631\u0627\u062c\u0639\u0629 \u0645\u062d\u062a\u0648\u0649 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u062c\u0646\u0633\u064a\u0629\u060c \u0631\u0623\u064a\u062a \u0643\u064a\u0641 \u064a\u0645\u0643\u0646 \u0644\u0639\u0628\u0627\u0631\u0629 \u0648\u0627\u062d\u062f\u0629 \u0639\u0644\u0649 \u0627\u0644\u0625\u0646\u062a\u0631\u0646\u062a \u0623\u0646 \u062a\u062e\u0644\u0637 \u0628\u064a\u0646 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0645\u0648\u062b\u0648\u0642 \u0648\u0628\u064a\u0646 \u0627\u0644\u0648\u0635\u0641\u0627\u062a \u0627\u0644\u0639\u0634\u0648\u0627\u0626\u064a\u0629\u060c \u0648\u0628\u064a\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062d\u0642\u064a\u0642\u064a \u0648\u0628\u064a\u0646 \u0627\u0644\u062a\u0633\u0648\u064a\u0642 \u0627\u0644\u0645\u0642\u0646\u0651\u0639.<\/p>\n

\u0645\u0646 \u0645\u0646\u0638\u0648\u0631 \u0637\u0628\u064a\u060c \u201c\u0623\u0641\u0636\u0644 \u062d\u0628\u0648\u0628 \u0644\u0644\u0627\u0646\u062a\u0635\u0627\u0628\u201d \u0644\u0627 \u062a\u0639\u0646\u064a \u0627\u0644\u0623\u0642\u0648\u0649 \u0623\u0648 \u0627\u0644\u0623\u0633\u0631\u0639 \u0623\u0648 \u0627\u0644\u0623\u063a\u0644\u0649. \u0627\u0644\u0623\u0641\u0636\u0644 \u0647\u0648 \u0645\u0627 \u064a\u0637\u0627\u0628\u0642 \u0633\u0628\u0628 \u0627\u0644\u0645\u0634\u0643\u0644\u0629\u060c \u0648\u064a\u062a\u0648\u0627\u0641\u0642 \u0645\u0639 \u062a\u0627\u0631\u064a\u062e\u0643 \u0627\u0644\u0635\u062d\u064a \u0648\u0623\u062f\u0648\u064a\u062a\u0643 \u0627\u0644\u0623\u062e\u0631\u0649\u060c \u0648\u064a\u064f\u0633\u062a\u062e\u062f\u0645 \u0636\u0645\u0646 \u0625\u0637\u0627\u0631 \u0622\u0645\u0646. \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0628\u0634\u0631\u064a \u0641\u0648\u0636\u0648\u064a \u0623\u062d\u064a\u0627\u0646\u064b\u0627\u061b \u0646\u0641\u0633 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0630\u064a \u064a\u0639\u0637\u064a \u0646\u062a\u064a\u062c\u0629 \u0645\u0645\u062a\u0627\u0632\u0629 \u0644\u0634\u062e\u0635 \u0642\u062f \u064a\u0633\u0628\u0628 \u0635\u062f\u0627\u0639\u064b\u0627 \u0645\u0632\u0639\u062c\u064b\u0627 \u0644\u0622\u062e\u0631\u060c \u0623\u0648 \u0644\u0627 \u064a\u0639\u0637\u064a \u0623\u064a \u0641\u0627\u0626\u062f\u0629 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0627\u0644\u0633\u0628\u0628 \u0646\u0641\u0633\u064a\u064b\u0627 \u0628\u062d\u062a\u064b\u0627 \u0623\u0648 \u0648\u0639\u0627\u0626\u064a\u064b\u0627 \u0645\u062a\u0642\u062f\u0645\u064b\u0627.<\/p>\n

\u0647\u0630\u0647 \u0627\u0644\u0645\u0642\u0627\u0644\u0629 \u062a\u0634\u0631\u062d \u0627\u0644\u062e\u064a\u0627\u0631\u0627\u062a \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629 \u0627\u0644\u0623\u0643\u062b\u0631 \u0627\u0639\u062a\u0645\u0627\u062f\u064b\u0627 \u0644\u0639\u0644\u0627\u062c \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628<\/em>\u060c \u0645\u0639 \u0641\u0635\u0644 \u0648\u0627\u0636\u062d \u0628\u064a\u0646 \u0627\u0644\u062d\u0642\u0627\u0626\u0642 \u0648\u0627\u0644\u0623\u0633\u0627\u0637\u064a\u0631. \u0633\u062a\u062c\u062f \u0634\u0631\u062d\u064b\u0627 \u0645\u0628\u0633\u0637\u064b\u0627 \u0644\u0622\u0644\u064a\u0629 \u0627\u0644\u0639\u0645\u0644\u060c \u0648\u0645\u062a\u0649 \u062a\u0643\u0648\u0646 \u0627\u0644\u062d\u0628\u0648\u0628 \u0645\u0646\u0637\u0642\u064a\u0629\u060c \u0648\u0645\u062a\u0649 \u062a\u0643\u0648\u0646 \u0645\u0636\u064a\u0639\u0629 \u0644\u0644\u0648\u0642\u062a \u0623\u0648 \u0645\u062e\u0627\u0637\u0631\u0629. \u0633\u0623\u0645\u0631\u0651 \u0623\u064a\u0636\u064b\u0627 \u0639\u0644\u0649 \u0627\u0644\u0633\u064a\u0627\u0642 \u0627\u0644\u062a\u0627\u0631\u064a\u062e\u064a \u0648\u0627\u0644\u0627\u062c\u062a\u0645\u0627\u0639\u064a: \u0643\u064a\u0641 \u062a\u062d\u0648\u0651\u0644 \u0627\u0644\u0645\u0648\u0636\u0648\u0639 \u0645\u0646 \u201c\u0639\u064a\u0628\u201d \u0625\u0644\u0649 \u062d\u0627\u0644\u0629 \u0637\u0628\u064a\u0629 \u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u0646\u0642\u0627\u0634\u060c \u0648\u0643\u064a\u0641 \u0641\u062a\u062d\u062a \u0627\u0644\u0634\u0647\u0631\u0629 \u0627\u0644\u0628\u0627\u0628 \u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0645\u0642\u0644\u0651\u062f\u0629 \u0648\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0645\u0636\u0644\u0644\u0629.<\/p>\n

\u062a\u0646\u0628\u064a\u0647 \u0645\u0628\u0643\u0631 \u0648\u0635\u0631\u064a\u062d: \u0644\u0646 \u0623\u0630\u0643\u0631 \u062c\u0631\u0639\u0627\u062a<\/strong> \u0623\u0648 \u201c\u0637\u0631\u064a\u0642\u0629 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062e\u0637\u0648\u0629 \u0628\u062e\u0637\u0648\u0629\u201d. \u0647\u0630\u0627 \u0644\u064a\u0633 \u062a\u0647\u0631\u0651\u0628\u064b\u0627\u061b \u0628\u0644 \u0644\u0623\u0646 \u0627\u0644\u062c\u0631\u0639\u0627\u062a \u062a\u062a\u063a\u064a\u0631 \u062d\u0633\u0628 \u0627\u0644\u0639\u0645\u0631\u060c \u0648\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0643\u0644\u0649 \u0648\u0627\u0644\u0643\u0628\u062f\u060c \u0648\u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0645\u0635\u0627\u062d\u0628\u0629\u060c \u0648\u062e\u0637\u0631 \u0647\u0628\u0648\u0637 \u0627\u0644\u0636\u063a\u0637. \u0627\u0644\u0647\u062f\u0641 \u0647\u0646\u0627 \u0645\u0639\u0631\u0641\u0629 \u0627\u0644\u062e\u064a\u0627\u0631\u0627\u062a \u0648\u0641\u0647\u0645\u0647\u0627\u060c \u062b\u0645 \u0645\u0646\u0627\u0642\u0634\u062a\u0647\u0627 \u0645\u0639 \u0637\u0628\u064a\u0628 \u0623\u0648 \u0635\u064a\u062f\u0644\u064a \u0645\u0624\u0647\u0644. \u0625\u0630\u0627 \u0623\u0631\u062f\u062a \u062e\u0644\u0641\u064a\u0629 \u0623\u0648\u0633\u0639 \u0639\u0646 \u0627\u0644\u0623\u0633\u0628\u0627\u0628 \u063a\u064a\u0631 \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629\u060c \u0633\u062a\u0641\u064a\u062f\u0643 \u0642\u0631\u0627\u0621\u0629 \u0623\u0633\u0628\u0627\u0628 \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0627\u0644\u0634\u0627\u0626\u0639\u0629<\/a>.<\/p>\n

\u0627\u0644\u062a\u0637\u0628\u064a\u0642\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0629: \u0645\u0627 \u0627\u0644\u0630\u064a \u062a\u0639\u0627\u0644\u062c\u0647 \u062d\u0628\u0648\u0628 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0641\u0639\u0644\u064a\u064b\u0627\u061f<\/h2>\n

\u0623\u063a\u0644\u0628 \u0645\u0627 \u064a\u064f\u0642\u0635\u062f \u0628\u0640 \u201c\u062d\u0628\u0648\u0628 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628\u201d \u0637\u0628\u064a\u064b\u0627 \u0647\u0648 \u0641\u0626\u0629 \u062f\u0648\u0627\u0626\u064a\u0629 \u0627\u0633\u0645\u0647\u0627 \u0645\u062b\u0628\u0637\u0627\u062a \u0625\u0646\u0632\u064a\u0645 PDE5<\/strong> (Phosphodiesterase type 5 inhibitors). \u0623\u0634\u0647\u0631 \u0627\u0644\u0623\u0633\u0645\u0627\u0621 \u0627\u0644\u0639\u0644\u0645\u064a\u0629 (\u0627\u0644\u062c\u0646\u064a\u0633\u0629\/\u0627\u0644\u062f\u0648\u0644\u064a\u0629) \u0647\u064a: \u0633\u064a\u0644\u062f\u064a\u0646\u0627\u0641\u064a\u0644<\/strong> (Sildenafil<\/a>)\u060c \u062a\u0627\u062f\u0627\u0644\u0627\u0641\u064a\u0644<\/strong> (Tadalafil)\u060c \u0641\u0627\u0631\u062f\u064a\u0646\u0627\u0641\u064a\u0644<\/strong> (Vardenafil)\u060c \u0648\u0623\u0641\u0627\u0646\u0627\u0641\u064a\u0644<\/strong> (Avanafil). \u0623\u0645\u0627 \u0627\u0644\u0623\u0633\u0645\u0627\u0621 \u0627\u0644\u062a\u062c\u0627\u0631\u064a\u0629 \u0627\u0644\u0623\u0643\u062b\u0631 \u062a\u062f\u0627\u0648\u0644\u064b\u0627 \u0639\u0627\u0644\u0645\u064a\u064b\u0627 \u0641\u062a\u0634\u0645\u0644: Viagra<\/em> \u0648Cialis<\/em> \u0648Levitra<\/em> \u0648Stendra<\/em>\u060c \u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0639\u0634\u0631\u0627\u062a \u0627\u0644\u0623\u0633\u0645\u0627\u0621 \u0627\u0644\u062c\u0646\u064a\u0633\u0629 \u062d\u0633\u0628 \u0627\u0644\u0628\u0644\u062f.<\/p>\n

\u0641\u064a \u0627\u0644\u0639\u064a\u0627\u062f\u0629\u060c \u0623\u0633\u0645\u0639 \u0643\u062b\u064a\u0631\u064b\u0627 \u0633\u0624\u0627\u0644\u064b\u0627 \u0645\u0628\u0627\u0634\u0631\u064b\u0627: \u201c\u0623\u064a\u0647\u0645 \u0627\u0644\u0623\u0641\u0636\u0644\u061f\u201d \u0648\u0623\u0631\u062f\u0651 \u0639\u0627\u062f\u0629 \u0628\u0633\u0624\u0627\u0644\u064a\u0646: \u0645\u0627 \u0633\u0628\u0628 \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628\u061f \u0648\u0645\u0627 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u062a\u0646\u0627\u0648\u0644\u0647\u0627\u061f \u0644\u0623\u0646 \u201c\u0627\u0644\u0623\u0641\u0636\u0644\u201d \u064a\u062a\u0628\u062f\u0651\u0644 \u0628\u0633\u0631\u0639\u0629 \u0639\u0646\u062f\u0645\u0627 \u064a\u062f\u062e\u0644 \u0641\u064a \u0627\u0644\u0635\u0648\u0631\u0629 \u0645\u0631\u0636 \u0627\u0644\u0642\u0644\u0628\u060c \u0623\u0648 \u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0630\u0628\u062d\u0629\u060c \u0623\u0648 \u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u063a\u064a\u0631 \u0645\u0636\u0628\u0648\u0637\u060c \u0623\u0648 \u0642\u0644\u0642 \u0634\u062f\u064a\u062f\u060c \u0623\u0648 \u0633\u0643\u0631\u064a \u0637\u0648\u064a\u0644 \u0627\u0644\u0623\u0645\u062f.<\/p>\n

2.1 \u0627\u0644\u0627\u0633\u062a\u0637\u0628\u0627\u0628 \u0627\u0644\u0623\u0633\u0627\u0633\u064a (Primary Use): \u0639\u0644\u0627\u062c \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628<\/h3>\n

\u0627\u0644\u0627\u0633\u062a\u0637\u0628\u0627\u0628 \u0627\u0644\u0623\u0633\u0627\u0633\u064a<\/strong> \u0644\u0645\u062b\u0628\u0637\u0627\u062a PDE5 \u0647\u0648 \u0639\u0644\u0627\u062c \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628<\/strong>\u060c \u0623\u064a \u0635\u0639\u0648\u0628\u0629 \u0627\u0644\u0648\u0635\u0648\u0644 \u0625\u0644\u0649 \u0627\u0646\u062a\u0635\u0627\u0628 \u0643\u0627\u0641\u064d \u0623\u0648 \u0627\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u064a\u0647 \u0628\u0645\u0627 \u064a\u0633\u0645\u062d \u0628\u0639\u0644\u0627\u0642\u0629 \u062c\u0646\u0633\u064a\u0629 \u0645\u064f\u0631\u0636\u064a\u0629. \u0647\u0630\u0647 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0644\u0627 \u201c\u062a\u0635\u0646\u0639 \u0627\u0644\u0631\u063a\u0628\u0629\u201d \u0645\u0646 \u0627\u0644\u0639\u062f\u0645\u060c \u0648\u0644\u0627 \u062a\u063a\u064a\u0651\u0631 \u0627\u0644\u0645\u0634\u0627\u0639\u0631\u060c \u0648\u0644\u0627 \u062a\u0639\u0627\u0644\u062c \u0627\u0644\u062e\u0644\u0627\u0641\u0627\u062a \u0627\u0644\u0632\u0648\u062c\u064a\u0629. \u0647\u064a \u062a\u0639\u0645\u0644 \u0639\u0644\u0649 \u062c\u0627\u0646\u0628 \u0645\u062d\u062f\u062f: \u062a\u062d\u0633\u064a\u0646 \u062a\u062f\u0641\u0642 \u0627\u0644\u062f\u0645 \u062f\u0627\u062e\u0644 \u0627\u0644\u0642\u0636\u064a\u0628 \u0639\u0646\u062f\u0645\u0627 \u062a\u0643\u0648\u0646 \u0647\u0646\u0627\u0643 \u0625\u062b\u0627\u0631\u0629 \u062c\u0646\u0633\u064a\u0629.<\/p>\n

\u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0644\u064a\u0633 \u062a\u0634\u062e\u064a\u0635\u064b\u0627 \u0648\u0627\u062d\u062f\u064b\u0627. \u0623\u062d\u064a\u0627\u0646\u064b\u0627 \u064a\u0643\u0648\u0646 \u0625\u0646\u0630\u0627\u0631\u064b\u0627 \u0645\u0628\u0643\u0631\u064b\u0627 \u0644\u0645\u0634\u0643\u0644\u0627\u062a \u0648\u0639\u0627\u0626\u064a\u0629 \u0623\u0648\u0633\u0639. \u0641\u064a \u062e\u0628\u0631\u062a\u064a\u060c \u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u0631\u062c\u0627\u0644 \u064a\u0623\u062a\u0648\u0646 \u0628\u062d\u062b\u064b\u0627 \u0639\u0646 \u062d\u0644 \u0633\u0631\u064a\u0639\u060c \u062b\u0645 \u0646\u0643\u062a\u0634\u0641 \u0623\u0646 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0645\u0631\u062a\u0641\u0639 \u0645\u0646\u0630 \u0633\u0646\u0648\u0627\u062a \u0623\u0648 \u0623\u0646 \u0627\u0644\u0633\u0643\u0631\u064a \u063a\u064a\u0631 \u0645\u0636\u0628\u0648\u0637. \u0647\u0646\u0627 \u062a\u0635\u0628\u062d \u0627\u0644\u062d\u0628\u0629 \u062c\u0632\u0621\u064b\u0627 \u0645\u0646 \u0627\u0644\u0635\u0648\u0631\u0629\u060c \u0644\u0627 \u0627\u0644\u0635\u0648\u0631\u0629 \u0643\u0644\u0647\u0627. \u0648\u0641\u064a \u062d\u0627\u0644\u0627\u062a \u0623\u062e\u0631\u0649 \u064a\u0643\u0648\u0646 \u0627\u0644\u0633\u0628\u0628 \u0646\u0641\u0633\u064a\u064b\u0627 (\u0642\u0644\u0642 \u0627\u0644\u0623\u062f\u0627\u0621\u060c \u0627\u0643\u062a\u0626\u0627\u0628\u060c \u062a\u0648\u062a\u0631 \u0645\u0632\u0645\u0646)\u060c \u0623\u0648 \u062f\u0648\u0627\u0626\u064a\u064b\u0627 (\u0628\u0639\u0636 \u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u0627\u0643\u062a\u0626\u0627\u0628\u060c \u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0628\u0631\u0648\u0633\u062a\u0627\u062a\u0627\u060c \u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0636\u063a\u0637)\u060c \u0623\u0648 \u0647\u0631\u0645\u0648\u0646\u064a\u064b\u0627 (\u0646\u0642\u0635 \u0627\u0644\u062a\u0633\u062a\u0648\u0633\u062a\u064a\u0631\u0648\u0646)\u060c \u0623\u0648 \u0639\u0635\u0628\u064a\u064b\u0627.<\/p>\n

\u0627\u0644\u062d\u062f\u0648\u062f \u0627\u0644\u0648\u0627\u0642\u0639\u064a\u0629 \u0645\u0647\u0645\u0629. \u0645\u062b\u0628\u0637\u0627\u062a PDE5 \u0644\u0627 \u062a\u0639\u0627\u0644\u062c \u0627\u0644\u0633\u0628\u0628 \u0627\u0644\u062c\u0630\u0631\u064a \u0625\u0630\u0627 \u0643\u0627\u0646 \u0647\u0646\u0627\u0643 \u062a\u0636\u064a\u0642 \u0634\u062f\u064a\u062f \u0641\u064a \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646 \u0623\u0648 \u062a\u0644\u0641 \u0639\u0635\u0628\u064a \u0645\u062a\u0642\u062f\u0645. \u0643\u0630\u0644\u0643 \u0644\u0627 \u062a\u0645\u0646\u062d \u201c\u0627\u0646\u062a\u0635\u0627\u0628\u064b\u0627 \u062f\u0627\u0626\u0645\u064b\u0627\u201d \u0648\u0644\u0627 \u062a\u0636\u0645\u0646 \u0646\u062c\u0627\u062d\u064b\u0627 \u0641\u064a \u0643\u0644 \u0645\u0631\u0629. \u0627\u0644\u0645\u0631\u0636\u0649 \u064a\u062e\u0628\u0631\u0648\u0646\u0646\u064a \u0623\u062d\u064a\u0627\u0646\u064b\u0627: \u201c\u0623\u062e\u0630\u062a\u0647\u0627 \u0648\u0644\u0645 \u064a\u062d\u062f\u062b \u0634\u064a\u0621.\u201d \u0648\u0639\u0646\u062f\u0645\u0627 \u0646\u0631\u0627\u062c\u0639 \u0627\u0644\u062a\u0641\u0627\u0635\u064a\u0644 \u0646\u062c\u062f \u063a\u064a\u0627\u0628 \u0627\u0644\u0625\u062b\u0627\u0631\u0629\u060c \u0623\u0648 \u062a\u0648\u0642\u064a\u062a\u064b\u0627 \u063a\u064a\u0631 \u0645\u0646\u0627\u0633\u0628\u060c \u0623\u0648 \u062a\u0646\u0627\u0648\u0644 \u0643\u062d\u0648\u0644 \u0628\u0643\u062b\u0631\u0629\u060c \u0623\u0648 \u062a\u0648\u0642\u0639\u0627\u062a \u063a\u064a\u0631 \u0648\u0627\u0642\u0639\u064a\u0629 \u0645\u0646 \u0627\u0644\u0623\u0633\u0627\u0633.<\/p>\n

\u0645\u0646 \u0627\u0644\u0646\u0627\u062d\u064a\u0629 \u0627\u0644\u0639\u0645\u0644\u064a\u0629\u060c \u0627\u0644\u0627\u062e\u062a\u0644\u0627\u0641\u0627\u062a \u0628\u064a\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u062f\u0627\u062e\u0644 \u0627\u0644\u0641\u0626\u0629 \u062a\u062a\u0639\u0644\u0642 \u0628\u0633\u0631\u0639\u0629 \u0628\u062f\u0621 \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0648\u0645\u062f\u0629 \u0628\u0642\u0627\u0626\u0647 \u0648\u0627\u062d\u062a\u0645\u0627\u0644 \u0628\u0639\u0636 \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629. \u062a\u0627\u062f\u0627\u0644\u0627\u0641\u064a\u0644 \u0645\u062b\u0644\u064b\u0627 \u0645\u0639\u0631\u0648\u0641 \u0628\u0645\u062f\u0629 \u0623\u0637\u0648\u0644\u060c \u0628\u064a\u0646\u0645\u0627 \u0633\u064a\u0644\u062f\u064a\u0646\u0627\u0641\u064a\u0644 \u0648\u0641\u0627\u0631\u062f\u064a\u0646\u0627\u0641\u064a\u0644 \u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u062a\u0643\u0648\u0646 \u0646\u0627\u0641\u0630\u062a\u0647\u0645\u0627 \u0623\u0642\u0635\u0631. \u0623\u0641\u0627\u0646\u0627\u0641\u064a\u0644 \u0635\u064f\u0645\u0645 \u0644\u064a\u0643\u0648\u0646 \u0623\u0643\u062b\u0631 \u0627\u0646\u062a\u0642\u0627\u0626\u064a\u0629 \u0646\u0633\u0628\u064a\u064b\u0627. \u0647\u0630\u0647 \u0641\u0631\u0648\u0642 \u0639\u0627\u0645\u0629\u060c \u0648\u0644\u064a\u0633\u062a \u062f\u0639\u0648\u0629 \u0644\u0627\u062e\u062a\u064a\u0627\u0631 \u0630\u0627\u062a\u064a \u062f\u0648\u0646 \u062a\u0642\u064a\u064a\u0645.<\/p>\n

\u0643\u064a\u0641 \u064a\u062e\u062a\u0627\u0631 \u0627\u0644\u0623\u0637\u0628\u0627\u0621 \u0628\u064a\u0646 \u0633\u064a\u0644\u062f\u064a\u0646\u0627\u0641\u064a\u0644 \u0648\u062a\u0627\u062f\u0627\u0644\u0627\u0641\u064a\u0644 \u0648\u0641\u0627\u0631\u062f\u064a\u0646\u0627\u0641\u064a\u0644 \u0648\u0623\u0641\u0627\u0646\u0627\u0641\u064a\u0644\u061f<\/h3>\n

\u0644\u0627 \u062a\u0648\u062c\u062f \u0625\u062c\u0627\u0628\u0629 \u0648\u0627\u062d\u062f\u0629 \u062a\u0635\u0644\u062d \u0644\u0644\u062c\u0645\u064a\u0639. \u0627\u0644\u0637\u0628\u064a\u0628 \u064a\u0646\u0638\u0631 \u0625\u0644\u0649 \u0646\u0645\u0637 \u0627\u0644\u062d\u064a\u0627\u0629\u060c \u0648\u062a\u0648\u0642\u064a\u062a \u0627\u0644\u0639\u0644\u0627\u0642\u0629\u060c \u0648\u0627\u0644\u062a\u0627\u0631\u064a\u062e \u0627\u0644\u0642\u0644\u0628\u064a \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u060c \u0648\u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0645\u0635\u0627\u062d\u0628\u0629\u060c \u0648\u0627\u0644\u062a\u062d\u0645\u0644 \u0644\u0644\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629. \u0623\u062d\u064a\u0627\u0646\u064b\u0627 \u064a\u0643\u0648\u0646 \u0627\u0644\u0642\u0631\u0627\u0631 \u0628\u0633\u064a\u0637\u064b\u0627: \u0634\u062e\u0635 \u0644\u062f\u064a\u0647 \u0635\u062f\u0627\u0639 \u0634\u062f\u064a\u062f \u0645\u0639 \u062f\u0648\u0627\u0621 \u0645\u0639\u064a\u0646 \u0641\u064a\u064f\u062c\u0631\u0651\u064e\u0628 \u0628\u062f\u064a\u0644 \u0645\u0646 \u0646\u0641\u0633 \u0627\u0644\u0641\u0626\u0629. \u0648\u0623\u062d\u064a\u0627\u0646\u064b\u0627 \u064a\u0643\u0648\u0646 \u0627\u0644\u0642\u0631\u0627\u0631 \u062d\u0633\u0627\u0633\u064b\u0627: \u0634\u062e\u0635 \u064a\u062a\u0646\u0627\u0648\u0644 \u0623\u062f\u0648\u064a\u0629 \u0646\u062a\u0631\u0627\u062a \u0644\u0644\u0630\u0628\u062d\u0629 \u0627\u0644\u0635\u062f\u0631\u064a\u0629\u060c \u0648\u0647\u0646\u0627 \u062a\u0635\u0628\u062d \u0645\u062b\u0628\u0637\u0627\u062a PDE5 \u063a\u064a\u0631 \u0645\u0646\u0627\u0633\u0628\u0629 \u0623\u0633\u0627\u0633\u064b\u0627 \u0628\u0633\u0628\u0628 \u062e\u0637\u0631 \u0647\u0628\u0648\u0637 \u0636\u063a\u0637 \u062e\u0637\u064a\u0631.<\/p>\n

\u0641\u064a \u0639\u0645\u0644\u064a \u0627\u0644\u062a\u062d\u0631\u064a\u0631\u064a\u060c \u0623\u0631\u0627\u062c\u0639 \u0643\u062b\u064a\u0631\u064b\u0627 \u0645\u062d\u062a\u0648\u0649 \u064a\u062e\u062a\u0632\u0644 \u0627\u0644\u0645\u0648\u0636\u0648\u0639 \u0641\u064a \u201c\u0627\u0644\u0623\u0642\u0648\u0649\u201d \u0648\u201c\u0627\u0644\u0623\u0633\u0631\u0639\u201d. \u0647\u0630\u0627 \u0627\u062e\u062a\u0632\u0627\u0644 \u0645\u0624\u0630\u064d. \u0627\u0644\u0623\u0641\u0636\u0644 \u0637\u0628\u064a\u064b\u0627 \u0647\u0648 \u0627\u0644\u0623\u0643\u062b\u0631 \u0623\u0645\u0627\u0646\u064b\u0627 \u0648\u0627\u0644\u0623\u0643\u062b\u0631 \u0645\u0644\u0627\u0621\u0645\u0629\u060c \u062d\u062a\u0649 \u0644\u0648 \u0643\u0627\u0646 \u0623\u0642\u0644 \u201c\u0634\u0647\u0631\u0629\u201d \u0639\u0644\u0649 \u0627\u0644\u0633\u0648\u0634\u064a\u0627\u0644 \u0645\u064a\u062f\u064a\u0627.<\/p>\n

2.2 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0627\u062a \u062b\u0627\u0646\u0648\u064a\u0629 \u0645\u0639\u062a\u0645\u062f\u0629 (Approved Secondary Uses)<\/h3>\n

\u0628\u0639\u0636 \u0623\u062f\u0648\u064a\u0629 \u0647\u0630\u0647 \u0627\u0644\u0641\u0626\u0629 \u0644\u0647\u0627 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0627\u062a \u0645\u0639\u062a\u0645\u062f\u0629 \u062e\u0627\u0631\u062c \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628. \u0627\u0644\u0645\u062b\u0627\u0644 \u0627\u0644\u0623\u0648\u0636\u062d \u0647\u0648 \u062a\u0627\u062f\u0627\u0644\u0627\u0641\u064a\u0644<\/strong>\u060c \u0625\u0630 \u064a\u064f\u0633\u062a\u062e\u062f\u0645 \u0623\u064a\u0636\u064b\u0627 \u0644\u0639\u0644\u0627\u062c \u0623\u0639\u0631\u0627\u0636 \u062a\u0636\u062e\u0645 \u0627\u0644\u0628\u0631\u0648\u0633\u062a\u0627\u062a\u0627 \u0627\u0644\u062d\u0645\u064a\u062f<\/strong> (Benign Prostatic Hyperplasia) \u0639\u0646\u062f \u0628\u0639\u0636 \u0627\u0644\u0645\u0631\u0636\u0649\u060c \u0644\u0623\u0646\u0647 \u064a\u0631\u062e\u0651\u064a \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0645\u0644\u0633\u0627\u0621 \u0641\u064a \u0627\u0644\u0628\u0631\u0648\u0633\u062a\u0627\u062a\u0627 \u0648\u0627\u0644\u0645\u062b\u0627\u0646\u0629 \u0648\u064a\u062d\u0633\u0646 \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u0628\u0648\u0644\u064a\u0629. \u0647\u0630\u0627 \u0644\u0627 \u064a\u0639\u0646\u064a \u0623\u0646\u0647 \u201c\u064a\u0639\u0627\u0644\u062c\u201d \u0627\u0644\u062a\u0636\u062e\u0645 \u0646\u0641\u0633\u0647\u060c \u0644\u0643\u0646\u0647 \u0642\u062f \u064a\u062e\u0641\u0641 \u0627\u0644\u0625\u0632\u0639\u0627\u062c \u0627\u0644\u064a\u0648\u0645\u064a \u0645\u062b\u0644 \u062a\u0643\u0631\u0627\u0631 \u0627\u0644\u062a\u0628\u0648\u0644 \u0623\u0648 \u0636\u0639\u0641 \u0627\u0646\u062f\u0641\u0627\u0639 \u0627\u0644\u0628\u0648\u0644.<\/p>\n

\u0623\u0645\u0627 \u0633\u064a\u0644\u062f\u064a\u0646\u0627\u0641\u064a\u0644<\/strong> \u0641\u0644\u0647 \u0634\u0643\u0644\/\u062a\u062d\u0636\u064a\u0631 \u062f\u0648\u0627\u0626\u064a \u0645\u0639\u062a\u0645\u062f \u0644\u0639\u0644\u0627\u062c \u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u0634\u0631\u064a\u0627\u0646 \u0627\u0644\u0631\u0626\u0648\u064a<\/strong> (Pulmonary Arterial Hypertension) \u062a\u062d\u062a \u0625\u0634\u0631\u0627\u0641 \u0627\u062e\u062a\u0635\u0627\u0635\u064a\u060c \u0628\u062c\u0631\u0639\u0627\u062a \u0648\u0646\u0638\u0627\u0645 \u0645\u062e\u062a\u0644\u0641\u064a\u0646 \u062a\u0645\u0627\u0645\u064b\u0627 \u0639\u0646 \u0633\u064a\u0627\u0642 \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628. \u0647\u0646\u0627 \u0623\u062a\u0648\u0642\u0641 \u062f\u0627\u0626\u0645\u064b\u0627 \u0639\u0646\u062f \u0646\u0642\u0637\u0629 \u0623\u0631\u0627\u0647\u0627 \u0641\u064a \u0627\u0644\u0648\u0627\u0642\u0639: \u0628\u0639\u0636 \u0627\u0644\u0646\u0627\u0633 \u064a\u0638\u0646\u0648\u0646 \u0623\u0646 \u0623\u064a \u0633\u064a\u0644\u062f\u064a\u0646\u0627\u0641\u064a\u0644 \u201c\u0647\u0648 \u0646\u0641\u0633\u0647\u201d \u0644\u0623\u064a \u063a\u0631\u0636. \u0644\u0627. \u0627\u062e\u062a\u0644\u0627\u0641 \u0627\u0644\u062a\u062d\u0636\u064a\u0631 \u0648\u0627\u0644\u062c\u0631\u0639\u0629 \u0648\u0627\u0644\u0633\u064a\u0627\u0642 \u0627\u0644\u0637\u0628\u064a \u0644\u064a\u0633 \u062a\u0641\u0635\u064a\u0644\u064b\u0627 \u0635\u063a\u064a\u0631\u064b\u0627.<\/p>\n

2.3 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0627\u062a \u062e\u0627\u0631\u062c \u0627\u0644\u0646\u0634\u0631\u0629 (Off-label) \u2014 \u0628\u062d\u0630\u0631 \u0634\u062f\u064a\u062f<\/h3>\n

\u0647\u0646\u0627\u0643 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0627\u062a \u062a\u064f\u0630\u0643\u0631 \u0641\u064a \u0627\u0644\u0623\u062f\u0628\u064a\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0629 \u062e\u0627\u0631\u062c \u0627\u0644\u0646\u0634\u0631\u0629 \u0644\u0628\u0639\u0636 \u0645\u062b\u0628\u0637\u0627\u062a PDE5\u060c \u0644\u0643\u0646 \u0627\u0644\u062a\u0639\u0627\u0645\u0644 \u0645\u0639\u0647\u0627 \u064a\u0643\u0648\u0646 \u0641\u0631\u062f\u064a\u064b\u0627 \u0648\u062a\u062d\u062a \u0625\u0634\u0631\u0627\u0641 \u0635\u0627\u0631\u0645. \u0645\u0646 \u0627\u0644\u0623\u0645\u062b\u0644\u0629 \u0627\u0644\u062a\u064a \u0642\u062f \u064a\u0646\u0627\u0642\u0634\u0647\u0627 \u0627\u0644\u0623\u0637\u0628\u0627\u0621 \u0641\u064a \u0633\u064a\u0627\u0642\u0627\u062a \u0645\u062d\u062f\u062f\u0629: \u0628\u0639\u0636 \u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0625\u0635\u0627\u0628\u0627\u062a \u0639\u0635\u0628\u064a\u0629\u060c \u0623\u0648 \u062d\u0627\u0644\u0627\u062a \u0645\u062e\u062a\u0627\u0631\u0629 \u0645\u0646 \u0638\u0627\u0647\u0631\u0629 \u0631\u064a\u0646\u0648 (Raynaud) \u0641\u064a \u0625\u0637\u0627\u0631 \u062a\u062c\u0627\u0631\u0628 \u0639\u0644\u0627\u062c\u064a\u0629\u060c \u0623\u0648 \u062f\u0639\u0645 \u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u062a\u0623\u0647\u064a\u0644 \u0627\u0644\u062c\u0646\u0633\u064a \u0628\u0639\u062f \u0628\u0639\u0636 \u0627\u0644\u062c\u0631\u0627\u062d\u0627\u062a. \u0647\u0630\u0647 \u0644\u064a\u0633\u062a \u201c\u0648\u0635\u0641\u0627\u062a \u0625\u0646\u062a\u0631\u0646\u062a\u201d. \u0647\u064a \u0642\u0631\u0627\u0631\u0627\u062a \u062a\u064f\u0628\u0646\u0649 \u0639\u0644\u0649 \u062a\u0642\u064a\u064a\u0645 \u0645\u062e\u0627\u0637\u0631 \u0648\u0641\u0648\u0627\u0626\u062f\u060c \u0648\u063a\u0627\u0644\u0628\u064b\u0627 \u0628\u0639\u062f \u0641\u0634\u0644 \u062e\u064a\u0627\u0631\u0627\u062a \u0623\u062e\u0631\u0649.<\/p>\n

\u0623\u0642\u0648\u0644\u0647\u0627 \u0643\u0645\u0627 \u0647\u064a: \u0639\u0646\u062f\u0645\u0627 \u0623\u0631\u0649 \u0634\u062e\u0635\u064b\u0627 \u064a\u0634\u062a\u0631\u064a \u062f\u0648\u0627\u0621\u064b \u201c\u0644\u062a\u062d\u0633\u064a\u0646 \u0627\u0644\u0623\u062f\u0627\u0621\u201d \u062f\u0648\u0646 \u062a\u0634\u062e\u064a\u0635 \u0648\u0627\u0636\u062d\u060c \u0623\u0634\u0639\u0631 \u0623\u0646 \u0627\u0644\u0642\u0635\u0629 \u0646\u0627\u0642\u0635\u0629. \u0623\u062d\u064a\u0627\u0646\u064b\u0627 \u064a\u0643\u0648\u0646 \u0648\u0631\u0627\u0621 \u0630\u0644\u0643 \u0642\u0644\u0642 \u0634\u062f\u064a\u062f \u0623\u0648 \u0636\u063a\u0637 \u0627\u062c\u062a\u0645\u0627\u0639\u064a \u0623\u0648 \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u062e\u0627\u0637\u0626\u0629. \u0627\u0644\u062d\u062f\u064a\u062b \u0627\u0644\u0635\u0631\u064a\u062d \u0645\u0639 \u0637\u0628\u064a\u0628 \u0642\u062f \u064a\u0648\u0641\u0631 \u0623\u0634\u0647\u0631\u064b\u0627 \u0645\u0646 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0639\u0634\u0648\u0627\u0626\u064a\u0629.<\/p>\n

2.4 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0627\u062a \u062a\u062c\u0631\u064a\u0628\u064a\u0629\/\u0646\u0627\u0634\u0626\u0629 (Experimental) \u2014 \u0623\u064a\u0646 \u064a\u0642\u0641 \u0627\u0644\u0639\u0644\u0645 \u0627\u0644\u0622\u0646\u061f<\/h3>\n

\u0627\u0644\u0628\u062d\u062b \u0627\u0644\u0639\u0644\u0645\u064a \u0644\u0627 \u064a\u062a\u0648\u0642\u0641\u060c \u0648\u0647\u0646\u0627\u0643 \u0627\u0647\u062a\u0645\u0627\u0645 \u0645\u0633\u062a\u0645\u0631 \u0628\u062f\u0631\u0627\u0633\u0629 \u062a\u0623\u062b\u064a\u0631\u0627\u062a \u0645\u062b\u0628\u0637\u0627\u062a PDE5 \u0639\u0644\u0649 \u0648\u0638\u0627\u0626\u0641 \u0648\u0639\u0627\u0626\u064a\u0629 \u0623\u062e\u0631\u0649\u060c \u0648\u0639\u0644\u0649 \u0628\u0639\u0636 \u062c\u0648\u0627\u0646\u0628 \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u062c\u0646\u0633\u064a\u0629 \u0648\u0627\u0644\u0625\u0646\u062c\u0627\u0628\u064a\u0629\u060c \u0648\u062d\u062a\u0649 \u0639\u0644\u0649 \u0645\u0624\u0634\u0631\u0627\u062a \u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629. \u0644\u0643\u0646 \u0648\u062c\u0648\u062f \u0641\u0631\u0636\u064a\u0629 \u0623\u0648 \u0646\u062a\u0627\u0626\u062c \u0623\u0648\u0644\u064a\u0629 \u0644\u0627 \u064a\u0639\u0646\u064a \u0648\u062c\u0648\u062f \u0639\u0644\u0627\u062c \u0645\u0639\u062a\u0645\u062f. \u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u062a\u0643\u0648\u0646 \u0635\u063a\u064a\u0631\u0629\u060c \u0623\u0648 \u0642\u0635\u064a\u0631\u0629 \u0627\u0644\u0645\u062f\u0649\u060c \u0623\u0648 \u0646\u062a\u0627\u0626\u062c\u0647\u0627 \u0645\u062a\u0628\u0627\u064a\u0646\u0629. \u0644\u0630\u0644\u0643\u060c \u0623\u064a \u062d\u062f\u064a\u062b \u0639\u0646 \u201c\u0641\u0648\u0627\u0626\u062f \u0625\u0636\u0627\u0641\u064a\u0629 \u0645\u0624\u0643\u062f\u0629\u201d \u062e\u0627\u0631\u062c \u0627\u0644\u0627\u0633\u062a\u0637\u0628\u0627\u0628\u0627\u062a \u0627\u0644\u0645\u0639\u062a\u0645\u062f\u0629 \u064a\u062d\u062a\u0627\u062c \u062a\u062f\u0642\u064a\u0642\u064b\u0627 \u0634\u062f\u064a\u062f\u064b\u0627.<\/p>\n

\u0625\u0630\u0627 \u0635\u0627\u062f\u0641\u062a \u0627\u062f\u0639\u0627\u0621\u064b \u0645\u062b\u0644 \u201c\u0647\u0630\u0647 \u0627\u0644\u062d\u0628\u0629 \u062a\u0646\u0638\u0641 \u0627\u0644\u0634\u0631\u0627\u064a\u064a\u0646\u201d \u0623\u0648 \u201c\u062a\u0639\u0627\u0644\u062c \u0627\u0644\u0639\u0642\u0645\u201d \u0623\u0648 \u201c\u062a\u0631\u0641\u0639 \u0627\u0644\u062a\u0633\u062a\u0648\u0633\u062a\u064a\u0631\u0648\u0646\u201d\u060c \u0641\u0627\u0639\u062a\u0628\u0631\u0647 \u0625\u0634\u0627\u0631\u0629 \u062d\u0645\u0631\u0627\u0621 \u062d\u062a\u0649 \u064a\u062b\u0628\u062a \u0627\u0644\u0639\u0643\u0633. \u0648\u0644\u0645\u0646 \u064a\u0631\u064a\u062f \u0641\u0647\u0645 \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064a\u0646 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0648\u0635\u062d\u0629 \u0627\u0644\u0642\u0644\u0628\u060c \u0623\u0646\u0635\u062d \u0628\u0645\u0631\u0627\u062c\u0639\u0629 \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0648\u0635\u062d\u0629 \u0627\u0644\u0642\u0644\u0628<\/a> \u0644\u0623\u0646\u0647\u0627 \u0632\u0627\u0648\u064a\u0629 \u064a\u063a\u0641\u0644\u0647\u0627 \u0643\u062b\u064a\u0631\u0648\u0646.<\/p>\n

\u0627\u0644\u0645\u062e\u0627\u0637\u0631 \u0648\u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629: \u0645\u0627 \u0627\u0644\u0630\u064a \u064a\u062c\u0628 \u0645\u0639\u0631\u0641\u062a\u0647 \u0642\u0628\u0644 \u0627\u0644\u062a\u0641\u0643\u064a\u0631 \u0641\u064a \u0627\u0644\u062d\u0628\u0648\u0628\u061f<\/h2>\n

\u0623\u064a \u062f\u0648\u0627\u0621 \u0641\u0639\u0651\u0627\u0644 \u0644\u0647 \u0622\u062b\u0627\u0631 \u062c\u0627\u0646\u0628\u064a\u0629 \u0645\u062d\u062a\u0645\u0644\u0629. \u0647\u0630\u0627 \u0644\u064a\u0633 \u062a\u062e\u0648\u064a\u0641\u064b\u0627\u061b \u0628\u0644 \u0648\u0627\u0642\u0639. \u0645\u0627 \u064a\u0632\u0639\u062c\u0646\u064a \u0641\u064a \u0627\u0644\u0645\u062d\u062a\u0648\u0649 \u0627\u0644\u0645\u0646\u062a\u0634\u0631 \u0623\u0646\u0647 \u064a\u0630\u0643\u0631 \u0627\u0644\u0641\u0648\u0627\u0626\u062f \u0628\u0635\u0648\u062a \u0639\u0627\u0644\u064d \u0648\u064a\u0647\u0645\u0633 \u0628\u0627\u0644\u0645\u062e\u0627\u0637\u0631. \u0628\u064a\u0646\u0645\u0627 \u0641\u064a \u0627\u0644\u0637\u0628\u060c \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u062c\u0632\u0621 \u0645\u0646 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629.<\/p>\n

3.1 \u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0627\u0644\u0634\u0627\u0626\u0639\u0629<\/h3>\n

\u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u0634\u0627\u0626\u0639\u0629 \u0644\u0645\u062b\u0628\u0637\u0627\u062a PDE5 \u062a\u0631\u062a\u0628\u0637 \u063a\u0627\u0644\u0628\u064b\u0627 \u0628\u062a\u0648\u0633\u0639 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u062a\u0623\u062b\u064a\u0631\u0647\u0627 \u0639\u0644\u0649 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0645\u0644\u0633\u0627\u0621. \u0645\u0646 \u0623\u0643\u062b\u0631 \u0645\u0627 \u064a\u064f\u0630\u0643\u0631: \u0627\u0644\u0635\u062f\u0627\u0639<\/strong>\u060c \u0627\u062d\u0645\u0631\u0627\u0631 \u0627\u0644\u0648\u062c\u0647<\/strong>\u060c \u0627\u062d\u062a\u0642\u0627\u0646 \u0627\u0644\u0623\u0646\u0641<\/strong>\u060c \u0639\u0633\u0631 \u0627\u0644\u0647\u0636\u0645<\/strong> \u0623\u0648 \u062d\u0631\u0642\u0629\u060c \u0648\u062f\u0648\u062e\u0629 \u062e\u0641\u064a\u0641\u0629<\/strong>. \u0628\u0639\u0636 \u0627\u0644\u0623\u0634\u062e\u0627\u0635 \u064a\u0635\u0641\u0648\u0646 \u0634\u0639\u0648\u0631\u064b\u0627 \u0628\u062b\u0642\u0644 \u0641\u064a \u0627\u0644\u0631\u0623\u0633 \u0623\u0648 \u062e\u0641\u0642\u0627\u0646\u064b\u0627 \u0628\u0633\u064a\u0637\u064b\u0627. \u0647\u0630\u0647 \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0624\u0642\u062a\u0629\u060c \u0644\u0643\u0646\u0647\u0627 \u0642\u062f \u062a\u0643\u0648\u0646 \u0645\u0632\u0639\u062c\u0629 \u0628\u0645\u0627 \u064a\u0643\u0641\u064a \u0644\u0625\u064a\u0642\u0627\u0641 \u0627\u0644\u062f\u0648\u0627\u0621 \u0623\u0648 \u062a\u063a\u064a\u064a\u0631\u0647.<\/p>\n

\u0647\u0646\u0627\u0643 \u0623\u064a\u0636\u064b\u0627 \u0623\u0639\u0631\u0627\u0636 \u062a\u062e\u062a\u0644\u0641 \u0628\u064a\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629: \u0633\u064a\u0644\u062f\u064a\u0646\u0627\u0641\u064a\u0644 \u0642\u062f \u064a\u0631\u062a\u0628\u0637 \u0628\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0628\u0635\u0631\u064a\u0629 \u0639\u0627\u0628\u0631\u0629 (\u0645\u062b\u0644 \u062a\u063a\u064a\u0631 \u062a\u0645\u064a\u064a\u0632 \u0627\u0644\u0623\u0644\u0648\u0627\u0646 \u0623\u0648 \u0636\u0628\u0627\u0628\u064a\u0629)\u060c \u0628\u064a\u0646\u0645\u0627 \u062a\u0627\u062f\u0627\u0644\u0627\u0641\u064a\u0644 \u0642\u062f \u064a\u0631\u062a\u0628\u0637 \u0628\u0622\u0644\u0627\u0645 \u0639\u0636\u0644\u064a\u0629 \u0623\u0648 \u0623\u0644\u0645 \u0623\u0633\u0641\u0644 \u0627\u0644\u0638\u0647\u0631 \u0644\u062f\u0649 \u0628\u0639\u0636 \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u064a\u0646. \u0644\u0627 \u0623\u062d\u0628 \u0627\u0644\u062a\u0639\u0645\u064a\u0645 \u0647\u0646\u0627\u061b \u0644\u0623\u0646 \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0627\u0644\u0641\u0631\u062f\u064a\u0629 \u0645\u062a\u0641\u0627\u0648\u062a\u0629 \u062c\u062f\u064b\u0627.<\/p>\n

\u0641\u064a \u0627\u0644\u0645\u0645\u0627\u0631\u0633\u0629 \u0627\u0644\u0648\u0627\u0642\u0639\u064a\u0629\u060c \u0623\u0631\u0649 \u0623\u0646 \u0627\u0644\u0645\u0634\u0643\u0644\u0629 \u0644\u064a\u0633\u062a \u0641\u064a \u0648\u062c\u0648\u062f \u0639\u0631\u0636 \u062c\u0627\u0646\u0628\u064a \u0628\u062d\u062f \u0630\u0627\u062a\u0647\u060c \u0628\u0644 \u0641\u064a \u062a\u062c\u0627\u0647\u0644\u0647 \u0623\u0648 \u062a\u0641\u0633\u064a\u0631\u0647 \u062e\u0637\u0623. \u0645\u0631\u064a\u0636 \u064a\u0642\u0648\u0644: \u201c\u0647\u0630\u0627 \u0637\u0628\u064a\u0639\u064a\u060c \u0633\u0623\u0636\u0627\u0639\u0641 \u0627\u0644\u062c\u0631\u0639\u0629.\u201d \u0647\u0646\u0627 \u062a\u0628\u062f\u0623 \u0627\u0644\u0645\u062a\u0627\u0639\u0628. \u0625\u0630\u0627 \u0638\u0647\u0631\u062a \u0623\u0639\u0631\u0627\u0636 \u0645\u0632\u0639\u062c\u0629\u060c \u0627\u0644\u0646\u0642\u0627\u0634 \u0645\u0639 \u0645\u062e\u062a\u0635 \u0647\u0648 \u0627\u0644\u0637\u0631\u064a\u0642 \u0627\u0644\u0623\u0642\u0635\u0631.<\/p>\n

3.2 \u0622\u062b\u0627\u0631 \u062c\u0627\u0646\u0628\u064a\u0629 \u062e\u0637\u064a\u0631\u0629 (\u0646\u0627\u062f\u0631\u0629 \u0644\u0643\u0646\u0647\u0627 \u0645\u0647\u0645\u0629)<\/h3>\n

\u0647\u0646\u0627\u0643 \u0622\u062b\u0627\u0631 \u0646\u0627\u062f\u0631\u0629 \u0644\u0643\u0646\u0647\u0627 \u062a\u0633\u062a\u062f\u0639\u064a \u0627\u0646\u062a\u0628\u0627\u0647\u064b\u0627 \u0641\u0648\u0631\u064a\u064b\u0627. \u0623\u0647\u0645\u0647\u0627 \u0647\u0628\u0648\u0637 \u0636\u063a\u0637 \u0634\u062f\u064a\u062f<\/strong> \u062e\u0635\u0648\u0635\u064b\u0627 \u0639\u0646\u062f \u0627\u0644\u062a\u062f\u0627\u062e\u0644 \u0645\u0639 \u0623\u062f\u0648\u064a\u0629 \u0645\u0639\u064a\u0646\u0629 (\u0633\u0623\u0630\u0643\u0631\u0647\u0627 \u0628\u0639\u062f \u0642\u0644\u064a\u0644). \u0643\u0630\u0644\u0643 \u062a\u0648\u062c\u062f \u062a\u0642\u0627\u0631\u064a\u0631 \u0646\u0627\u062f\u0631\u0629 \u0639\u0646 \u0627\u0646\u062a\u0635\u0627\u0628 \u0645\u0624\u0644\u0645 \u0623\u0648 \u0645\u0637\u0648\u0651\u0644<\/strong> (priapism) \u064a\u0633\u062a\u0645\u0631 \u0633\u0627\u0639\u0627\u062a\u061b \u0648\u0647\u0630\u0647 \u062d\u0627\u0644\u0629 \u0625\u0633\u0639\u0627\u0641\u064a\u0629 \u0644\u0623\u0646 \u0627\u0633\u062a\u0645\u0631\u0627\u0631\u0647\u0627 \u0642\u062f \u064a\u0633\u0628\u0628 \u0636\u0631\u0631\u064b\u0627 \u062f\u0627\u0626\u0645\u064b\u0627 \u0644\u0644\u0623\u0646\u0633\u062c\u0629.<\/p>\n

\u0623\u064a \u0623\u0644\u0645 \u0635\u062f\u0631\u064a<\/strong>\u060c \u0625\u063a\u0645\u0627\u0621<\/strong>\u060c \u0636\u064a\u0642 \u0646\u0641\u0633 \u0634\u062f\u064a\u062f<\/strong>\u060c \u0623\u0648 \u0636\u0639\u0641 \u0645\u0641\u0627\u062c\u0626 \u0641\u064a \u0627\u0644\u0631\u0624\u064a\u0629 \u0623\u0648 \u0627\u0644\u0633\u0645\u0639<\/strong> \u0628\u0639\u062f \u062a\u0646\u0627\u0648\u0644 \u0627\u0644\u062f\u0648\u0627\u0621 \u064a\u0633\u062a\u062f\u0639\u064a \u062a\u0642\u064a\u064a\u0645\u064b\u0627 \u0639\u0627\u062c\u0644\u064b\u0627. \u0644\u0627 \u0623\u062d\u0628 \u0644\u063a\u0629 \u0627\u0644\u0630\u0639\u0631\u060c \u0644\u0643\u0646\u0646\u064a \u0631\u0623\u064a\u062a \u0623\u0634\u062e\u0627\u0635\u064b\u0627 \u064a\u0624\u062e\u0631\u0648\u0646 \u0637\u0644\u0628 \u0627\u0644\u0645\u0633\u0627\u0639\u062f\u0629 \u0644\u0623\u0646\u0647\u0645 \u201c\u062e\u062c\u0644\u0648\u0627\u201d \u0645\u0646 \u0630\u0643\u0631 \u0633\u0628\u0628 \u062a\u0646\u0627\u0648\u0644 \u0627\u0644\u062f\u0648\u0627\u0621. \u0641\u064a \u0627\u0644\u0637\u0648\u0627\u0631\u0626\u060c \u0644\u0627 \u0623\u062d\u062f \u064a\u0647\u062a\u0645 \u0628\u0627\u0644\u0625\u062d\u0631\u0627\u062c\u061b \u064a\u0647\u062a\u0645\u0648\u0646 \u0628\u0633\u0644\u0627\u0645\u062a\u0643.<\/p>\n

3.3 \u0645\u0648\u0627\u0646\u0639 \u0627\u0644\u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u0648\u0627\u0644\u062a\u062f\u0627\u062e\u0644\u0627\u062a \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629<\/h3>\n

\u0623\u0647\u0645 \u0645\u0627\u0646\u0639 \u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u0639\u0645\u0644\u064a\u064b\u0627 \u0647\u0648 \u0627\u0644\u062c\u0645\u0639 \u0628\u064a\u0646 \u0645\u062b\u0628\u0637\u0627\u062a PDE5 \u0648\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0646\u062a\u0631\u0627\u062a<\/strong> \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u0629 \u0644\u0644\u0630\u0628\u062d\u0629 \u0627\u0644\u0635\u062f\u0631\u064a\u0629 (\u0645\u062b\u0644 \u0627\u0644\u0646\u064a\u062a\u0631\u0648\u063a\u0644\u064a\u0633\u0631\u064a\u0646 \u0648\u0623\u0634\u0643\u0627\u0644\u0647). \u0647\u0630\u0627 \u0627\u0644\u062a\u062f\u0627\u062e\u0644 \u0642\u062f \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0647\u0628\u0648\u0637 \u0636\u063a\u0637 \u062e\u0637\u064a\u0631. \u0643\u0630\u0644\u0643 \u064a\u062c\u0628 \u0627\u0644\u062d\u0630\u0631 \u0627\u0644\u0634\u062f\u064a\u062f \u0645\u0639 \u0628\u0639\u0636 \u0623\u062f\u0648\u064a\u0629 \u062d\u0627\u0635\u0631\u0627\u062a \u0623\u0644\u0641\u0627<\/strong> \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u0629 \u0644\u0644\u0628\u0631\u0648\u0633\u062a\u0627\u062a\u0627 \u0623\u0648 \u0627\u0644\u0636\u063a\u0637\u060c \u0644\u0623\u0646 \u0627\u0644\u062c\u0645\u0639 \u0642\u062f \u064a\u0632\u064a\u062f \u0627\u0644\u062f\u0648\u062e\u0629 \u0623\u0648 \u0647\u0628\u0648\u0637 \u0627\u0644\u0636\u063a\u0637\u060c \u0648\u064a\u062d\u062a\u0627\u062c \u062a\u0642\u064a\u064a\u0645\u064b\u0627 \u0637\u0628\u064a\u064b\u0627 \u062f\u0642\u064a\u0642\u064b\u0627.<\/p>\n

\u062a\u0648\u062c\u062f \u062a\u062f\u0627\u062e\u0644\u0627\u062a \u0623\u064a\u0636\u064b\u0627 \u0645\u0639 \u0623\u062f\u0648\u064a\u0629 \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0625\u0646\u0632\u064a\u0645\u0627\u062a \u0627\u0644\u0643\u0628\u062f \u0627\u0644\u0645\u0633\u0624\u0648\u0644\u0629 \u0639\u0646 \u0627\u0633\u062a\u0642\u0644\u0627\u0628 \u0647\u0630\u0647 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 (\u0645\u062b\u0644 \u0628\u0639\u0636 \u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u0641\u0637\u0631\u064a\u0627\u062a \u0623\u0648 \u0627\u0644\u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0623\u0648 \u0623\u062f\u0648\u064a\u0629 \u0641\u064a\u0631\u0648\u0633 \u0646\u0642\u0635 \u0627\u0644\u0645\u0646\u0627\u0639\u0629). \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0642\u062f \u062a\u0643\u0648\u0646 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062f\u0648\u0627\u0621 \u0641\u064a \u0627\u0644\u062f\u0645 \u0648\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0623\u0639\u0631\u0627\u0636. \u0648\u0641\u064a \u0627\u0644\u0627\u062a\u062c\u0627\u0647 \u0627\u0644\u0622\u062e\u0631\u060c \u0642\u062f \u062a\u0642\u0644 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0645\u0639 \u0623\u062f\u0648\u064a\u0629 \u0623\u062e\u0631\u0649.<\/p>\n

\u0627\u0644\u0643\u062d\u0648\u0644 \u0645\u0648\u0636\u0648\u0639 \u0645\u062a\u0643\u0631\u0631 \u0641\u064a \u0627\u0644\u0623\u0633\u0626\u0644\u0629. \u0627\u0644\u0643\u062d\u0648\u0644 \u0628\u062d\u062f \u0630\u0627\u062a\u0647 \u0642\u062f \u064a\u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0648\u064a\u0632\u064a\u062f \u0627\u0644\u062f\u0648\u062e\u0629 \u0648\u064a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0636\u063a\u0637\u060c \u0648\u0645\u0639 \u0627\u0644\u062f\u0648\u0627\u0621 \u0642\u062f \u062a\u0635\u0628\u062d \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0623\u0643\u062b\u0631 \u0625\u0632\u0639\u0627\u062c\u064b\u0627. \u0623\u0645\u0627 \u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u0645\u0646\u0628\u0647\u0629 \u0623\u0648 \u0627\u0644\u0645\u062e\u062f\u0631\u0627\u062a \u0641\u0627\u0644\u0645\u0639\u0627\u062f\u0644\u0629 \u062a\u0635\u0628\u062d \u063a\u064a\u0631 \u0645\u062a\u0648\u0642\u0639\u0629 \u0648\u062e\u0637\u0631\u0629\u060c \u062e\u0635\u0648\u0635\u064b\u0627 \u0639\u0644\u0649 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0636\u063a\u0637. \u0625\u0630\u0627 \u0623\u0631\u062f\u062a \u062a\u0641\u0635\u064a\u0644\u064b\u0627 \u0639\u0646 \u0627\u0644\u062a\u062f\u0627\u062e\u0644\u0627\u062a \u0627\u0644\u0634\u0627\u0626\u0639\u0629\u060c \u0633\u062a\u062c\u062f \u0645\u0627\u062f\u0629 \u0645\u0641\u064a\u062f\u0629 \u0628\u0639\u0646\u0648\u0627\u0646 \u0627\u0644\u062a\u062f\u0627\u062e\u0644\u0627\u062a \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629 \u0627\u0644\u0634\u0627\u0626\u0639\u0629 \u0641\u064a \u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628<\/a>.<\/p>\n

\u0645\u0627 \u0648\u0631\u0627\u0621 \u0627\u0644\u0637\u0628: \u0633\u0648\u0621 \u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645\u060c \u0627\u0644\u0623\u0633\u0627\u0637\u064a\u0631\u060c \u0648\u0633\u0648\u0621 \u0627\u0644\u0641\u0647\u0645 \u0627\u0644\u0639\u0627\u0645<\/h2>\n

\u0644\u0646\u0643\u0646 \u0648\u0627\u0642\u0639\u064a\u064a\u0646: \u0634\u0647\u0631\u0629 \u062d\u0628\u0648\u0628 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u062c\u0639\u0644\u062a\u0647\u0627 \u062c\u0632\u0621\u064b\u0627 \u0645\u0646 \u0627\u0644\u062b\u0642\u0627\u0641\u0629 \u0627\u0644\u0634\u0639\u0628\u064a\u0629. \u0648\u0647\u0630\u0627 \u0644\u0647 \u0648\u062c\u0647\u0627\u0646. \u0627\u0644\u0648\u062c\u0647 \u0627\u0644\u062c\u064a\u062f \u0623\u0646\u0647 \u0643\u0633\u0631 \u0627\u0644\u0635\u0645\u062a \u062d\u0648\u0644 \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628\u060c \u0648\u0627\u0644\u0648\u062c\u0647 \u0627\u0644\u0633\u064a\u0626 \u0623\u0646\u0647 \u0641\u062a\u062d \u0627\u0644\u0628\u0627\u0628 \u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062a\u0631\u0641\u064a\u0647\u064a\u060c \u0648\u062a\u0648\u0642\u0639\u0627\u062a \u062e\u064a\u0627\u0644\u064a\u0629\u060c \u0648\u0633\u0648\u0642 \u0645\u0648\u0627\u0632\u064a\u0629 \u0645\u0646 \u0645\u0646\u062a\u062c\u0627\u062a \u201c\u0637\u0628\u064a\u0639\u064a\u0629\u201d \u0645\u062c\u0647\u0648\u0644\u0629.<\/p>\n

4.1 \u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u063a\u064a\u0631 \u0627\u0644\u0637\u0628\u064a: \u0644\u0645\u0627\u0630\u0627 \u064a\u0646\u062c\u0630\u0628 \u0625\u0644\u064a\u0647 \u0627\u0644\u0628\u0639\u0636\u061f<\/h3>\n

\u0623\u0642\u0627\u0628\u0644 \u0623\u062d\u064a\u0627\u0646\u064b\u0627 \u0634\u0628\u0627\u0628\u064b\u0627 \u0628\u0644\u0627 \u0645\u0634\u0643\u0644\u0629 \u0637\u0628\u064a\u0629 \u0648\u0627\u0636\u062d\u0629\u060c \u0644\u0643\u0646\u0647\u0645 \u064a\u0631\u064a\u062f\u0648\u0646 \u201c\u0636\u0645\u0627\u0646 \u0627\u0644\u0623\u062f\u0627\u0621\u201d. \u0627\u0644\u0645\u0631\u0636\u0649 \u064a\u0642\u0648\u0644\u0648\u0646 \u0644\u064a: \u201c\u0623\u0631\u064a\u062f \u062b\u0642\u0629 \u0625\u0636\u0627\u0641\u064a\u0629.\u201d \u0623\u0641\u0647\u0645 \u0627\u0644\u062f\u0627\u0641\u0639\u060c \u0644\u0643\u0646\u0646\u064a \u0644\u0627 \u0623\u0635\u0641\u0647 \u0628\u0623\u0646\u0647 \u062e\u064a\u0627\u0631 \u0630\u0643\u064a. \u0644\u0623\u0646 \u0627\u0644\u0627\u0639\u062a\u0645\u0627\u062f \u0627\u0644\u0646\u0641\u0633\u064a \u0642\u062f \u064a\u062a\u0634\u0643\u0644 \u0628\u0633\u0631\u0639\u0629: \u064a\u0628\u062f\u0623 \u0627\u0644\u0634\u062e\u0635 \u0628\u0627\u0644\u0627\u0639\u062a\u0642\u0627\u062f \u0623\u0646\u0647 \u0644\u0627 \u064a\u0633\u062a\u0637\u064a\u0639 \u0627\u0644\u0623\u062f\u0627\u0621 \u062f\u0648\u0646 \u062d\u0628\u0629\u060c \u062d\u062a\u0649 \u0644\u0648 \u0643\u0627\u0646 \u062c\u0633\u062f\u0647 \u064a\u0639\u0645\u0644 \u062c\u064a\u062f\u064b\u0627.<\/p>\n

\u0647\u0646\u0627\u0643 \u0623\u064a\u0636\u064b\u0627 \u0645\u0646 \u064a\u0633\u062a\u062e\u062f\u0645\u0647\u0627 \u0644\u062a\u0639\u0648\u064a\u0636 \u0622\u062b\u0627\u0631 \u0627\u0644\u0643\u062d\u0648\u0644 \u0623\u0648 \u0627\u0644\u0633\u0647\u0631 \u0623\u0648 \u0627\u0644\u062a\u0648\u062a\u0631. \u0647\u0630\u0627 \u064a\u0634\u0628\u0647 \u0648\u0636\u0639 \u0634\u0631\u064a\u0637 \u0644\u0627\u0635\u0642 \u0639\u0644\u0649 \u0625\u0646\u0630\u0627\u0631 \u062d\u0631\u064a\u0642 \u0628\u062f\u0644 \u0625\u0637\u0641\u0627\u0621 \u0627\u0644\u0646\u0627\u0631. \u0642\u062f \u062a\u0645\u0631 \u0627\u0644\u0644\u064a\u0644\u0629\u060c \u0644\u0643\u0646 \u0627\u0644\u0645\u0634\u0643\u0644\u0629 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629 \u062a\u0628\u0642\u0649.<\/p>\n

4.2 \u062a\u0631\u0643\u064a\u0628\u0627\u062a \u063a\u064a\u0631 \u0622\u0645\u0646\u0629: \u0627\u0644\u0643\u062d\u0648\u0644\u060c \u0627\u0644\u0645\u0646\u0634\u0637\u0627\u062a\u060c \u0648\u0623\u062f\u0648\u064a\u0629 \u201c\u0627\u0644\u062a\u062e\u0633\u064a\u0633\u201d<\/h3>\n

\u0623\u0643\u062b\u0631 \u0645\u0627 \u064a\u0642\u0644\u0642\u0646\u064a \u0647\u0648 \u0627\u0644\u0645\u0632\u062c \u0627\u0644\u0639\u0634\u0648\u0627\u0626\u064a. \u0627\u0644\u062c\u0645\u0639 \u0628\u064a\u0646 \u0645\u062b\u0628\u0637\u0627\u062a PDE5 \u0648\u0645\u0648\u0627\u062f \u0645\u0646\u0628\u0647\u0629 (\u0633\u0648\u0627\u0621 \u0643\u0627\u0646\u062a \u0623\u062f\u0648\u064a\u0629 \u0645\u0646\u0634\u0637\u0629 \u0623\u0648 \u0645\u0648\u0627\u062f \u063a\u064a\u0631 \u0642\u0627\u0646\u0648\u0646\u064a\u0629) \u064a\u0631\u0641\u0639 \u0627\u0644\u0639\u0628\u0621 \u0639\u0644\u0649 \u0627\u0644\u0642\u0644\u0628 \u0648\u064a\u0632\u064a\u062f \u0627\u0636\u0637\u0631\u0627\u0628 \u0627\u0644\u0636\u063a\u0637. \u0643\u0630\u0644\u0643 \u062a\u0646\u062a\u0634\u0631 \u062e\u0644\u0637\u0627\u062a \u201c\u0642\u0628\u0644 \u0627\u0644\u0639\u0644\u0627\u0642\u0629\u201d \u0627\u0644\u062a\u064a \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0643\u0627\u0641\u064a\u064a\u0646 \u0639\u0627\u0644\u064a\u060c \u0623\u0648 \u0645\u0648\u0627\u062f \u0639\u0634\u0628\u064a\u0629 \u063a\u064a\u0631 \u0645\u0636\u0628\u0648\u0637\u0629\u060c \u0623\u0648 \u062d\u062a\u0649 \u0623\u062f\u0648\u064a\u0629 \u0645\u062e\u0641\u064a\u0629 \u062f\u0627\u062e\u0644 \u0643\u0628\u0633\u0648\u0644\u0627\u062a \u201c\u0637\u0628\u064a\u0639\u064a\u0629\u201d. \u0647\u0646\u0627 \u0644\u0627 \u062a\u0633\u062a\u0637\u064a\u0639 \u062a\u0648\u0642\u0639 \u0627\u0644\u062c\u0631\u0639\u0629 \u0648\u0644\u0627 \u0627\u0644\u062a\u062f\u0627\u062e\u0644\u0627\u062a.<\/p>\n

\u062d\u062a\u0649 \u0627\u0644\u0645\u0643\u0645\u0644\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0628\u062f\u0648 \u0628\u0631\u064a\u0626\u0629 \u0642\u062f \u062a\u0643\u0648\u0646 \u0645\u0634\u0643\u0644\u0629 \u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0645\u0644\u0648\u062b\u0629 \u0623\u0648 \u0645\u063a\u0634\u0648\u0634\u0629. \u0641\u064a \u0639\u0645\u0644\u064a\u060c \u0631\u0627\u062c\u0639\u062a \u062a\u0642\u0627\u0631\u064a\u0631 \u0645\u062e\u0628\u0631\u064a\u0629 \u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0627\u062f\u0639\u062a \u0623\u0646\u0647\u0627 \u0639\u0634\u0628\u064a\u0629 \u062b\u0645 \u0648\u064f\u062c\u062f \u0641\u064a\u0647\u0627 \u0633\u064a\u0644\u062f\u064a\u0646\u0627\u0641\u064a\u0644 \u0623\u0648 \u0645\u0634\u062a\u0642\u0627\u062a \u0642\u0631\u064a\u0628\u0629 \u0628\u062a\u0631\u0643\u064a\u0632\u0627\u062a \u063a\u064a\u0631 \u0645\u0639\u0644\u0648\u0645\u0629. \u0647\u0630\u0627 \u0644\u064a\u0633 \u062a\u0641\u0635\u064a\u0644\u064b\u0627\u061b \u0647\u0630\u0627 \u062e\u0637\u0631 \u0645\u0628\u0627\u0634\u0631.<\/p>\n

4.3 \u0623\u0633\u0627\u0637\u064a\u0631 \u0634\u0627\u0626\u0639\u0629 \u0648\u062a\u0635\u062d\u064a\u062d\u0647\u0627 \u0628\u0647\u062f\u0648\u0621<\/h3>\n
    \n
  • \u0627\u0644\u062e\u0631\u0627\u0641\u0629:<\/strong> \u201c\u062d\u0628\u0648\u0628 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u062a\u0632\u064a\u062f \u0627\u0644\u0631\u063a\u0628\u0629 \u0627\u0644\u062c\u0646\u0633\u064a\u0629.\u201d
    \u0627\u0644\u062a\u0635\u062d\u064a\u062d:<\/strong> \u0647\u064a \u062a\u062d\u0633\u0646 \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0644\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0639\u0646\u062f \u0648\u062c\u0648\u062f \u0625\u062b\u0627\u0631\u0629\u060c \u0644\u0643\u0646\u0647\u0627 \u0644\u0627 \u062a\u062e\u0644\u0642 \u0631\u063a\u0628\u0629 \u0645\u0646 \u0627\u0644\u0635\u0641\u0631.<\/li>\n
  • \u0627\u0644\u062e\u0631\u0627\u0641\u0629:<\/strong> \u201c\u0625\u0630\u0627 \u0644\u0645 \u062a\u0646\u062c\u062d \u0645\u0631\u0629\u060c \u0641\u0647\u064a \u0644\u0627 \u062a\u0635\u0644\u062d \u0623\u0628\u062f\u064b\u0627.\u201d
    \u0627\u0644\u062a\u0635\u062d\u064a\u062d:<\/strong> \u0627\u0644\u0641\u0634\u0644 \u0642\u062f \u064a\u0631\u062a\u0628\u0637 \u0628\u062a\u0648\u0642\u0639\u0627\u062a\u060c \u0623\u0648 \u0642\u0644\u0642\u060c \u0623\u0648 \u062a\u062f\u0627\u062e\u0644\u0627\u062a\u060c \u0623\u0648 \u0633\u0628\u0628 \u0645\u0631\u0636\u064a \u064a\u062d\u062a\u0627\u062c \u062a\u0634\u062e\u064a\u0635\u064b\u0627. \u0627\u0644\u062d\u0643\u0645 \u0627\u0644\u0633\u0631\u064a\u0639 \u064a\u0636\u0644\u0644.<\/li>\n
  • \u0627\u0644\u062e\u0631\u0627\u0641\u0629:<\/strong> \u201c\u0627\u0644\u0645\u0646\u062a\u062c \u0627\u0644\u0637\u0628\u064a\u0639\u064a \u062f\u0627\u0626\u0645\u064b\u0627 \u0622\u0645\u0646.\u201d
    \u0627\u0644\u062a\u0635\u062d\u064a\u062d:<\/strong> \u0627\u0644\u0637\u0628\u064a\u0639\u064a \u0642\u062f \u064a\u0643\u0648\u0646 \u063a\u064a\u0631 \u0645\u0636\u0628\u0648\u0637 \u0623\u0648 \u0645\u063a\u0634\u0648\u0634\u064b\u0627 \u0623\u0648 \u064a\u062a\u062f\u0627\u062e\u0644 \u0645\u0639 \u0623\u062f\u0648\u064a\u0629 \u0623\u062e\u0631\u0649. \u0643\u0644\u0645\u0629 \u201c\u0637\u0628\u064a\u0639\u064a\u201d \u0644\u064a\u0633\u062a \u0634\u0647\u0627\u062f\u0629 \u062c\u0648\u062f\u0629.<\/li>\n
  • \u0627\u0644\u062e\u0631\u0627\u0641\u0629:<\/strong> \u201c\u0643\u0644\u0645\u0627 \u0643\u0627\u0646\u062a \u0627\u0644\u062d\u0628\u0629 \u0623\u0642\u0648\u0649 \u0643\u0627\u0646 \u0630\u0644\u0643 \u0623\u0641\u0636\u0644.\u201d
    \u0627\u0644\u062a\u0635\u062d\u064a\u062d:<\/strong> \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0642\u0648\u0629 \u062a\u0639\u0646\u064a \u063a\u0627\u0644\u0628\u064b\u0627 \u0632\u064a\u0627\u062f\u0629 \u0622\u062b\u0627\u0631 \u062c\u0627\u0646\u0628\u064a\u0629 \u0648\u0645\u062e\u0627\u0637\u0631\u060c \u062e\u0635\u0648\u0635\u064b\u0627 \u0639\u0644\u0649 \u0627\u0644\u0636\u063a\u0637 \u0648\u0627\u0644\u0642\u0644\u0628.<\/li>\n<\/ul>\n

    \u0622\u0644\u064a\u0629 \u0627\u0644\u0639\u0645\u0644: \u0634\u0631\u062d \u0645\u0628\u0633\u0637 \u0644\u0643\u0646 \u062f\u0642\u064a\u0642<\/h2>\n

    \u0644\u0641\u0647\u0645 \u0644\u0645\u0627\u0630\u0627 \u062a\u0639\u0645\u0644 \u0647\u0630\u0647 \u0627\u0644\u0623\u062f\u0648\u064a\u0629\u060c \u0646\u062d\u062a\u0627\u062c \u062f\u0642\u064a\u0642\u0629 \u0641\u0633\u064a\u0648\u0644\u0648\u062c\u064a\u0627. \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0639\u0645\u0644\u064a\u0629 \u0648\u0639\u0627\u0626\u064a\u0629-\u0639\u0635\u0628\u064a\u0629: \u0639\u0646\u062f \u0627\u0644\u0625\u062b\u0627\u0631\u0629 \u0627\u0644\u062c\u0646\u0633\u064a\u0629 \u064a\u0641\u0631\u0632 \u0627\u0644\u062c\u0633\u0645 \u0623\u0643\u0633\u064a\u062f \u0627\u0644\u0646\u062a\u0631\u064a\u0643<\/strong> (Nitric Oxide) \u0641\u064a \u0623\u0646\u0633\u062c\u0629 \u0627\u0644\u0642\u0636\u064a\u0628. \u0647\u0630\u0627 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0632\u064a\u0627\u062f\u0629 \u0645\u0627\u062f\u0629 \u062f\u0627\u062e\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0633\u0645\u0647\u0627 cGMP<\/strong>\u060c \u0641\u062a\u0633\u062a\u0631\u062e\u064a \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0645\u0644\u0633\u0627\u0621 \u0641\u064a \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u062f\u0627\u062e\u0644 \u0627\u0644\u0642\u0636\u064a\u0628\u060c \u0648\u064a\u0632\u062f\u0627\u062f \u062a\u062f\u0641\u0642 \u0627\u0644\u062f\u0645\u060c \u0648\u062a\u064f\u062d\u062a\u062c\u0632 \u0643\u0645\u064a\u0629 \u0627\u0644\u062f\u0645 \u062f\u0627\u062e\u0644 \u0627\u0644\u0623\u062c\u0633\u0627\u0645 \u0627\u0644\u0643\u0647\u0641\u064a\u0629\u060c \u0641\u064a\u062d\u062f\u062b \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628.<\/p>\n

    \u0647\u0646\u0627 \u064a\u0623\u062a\u064a \u062f\u0648\u0631 \u0625\u0646\u0632\u064a\u0645 \u0627\u0633\u0645\u0647 PDE5<\/strong>\u060c \u0648\u0638\u064a\u0641\u062a\u0647 \u062a\u0643\u0633\u064a\u0631 cGMP. \u0639\u0646\u062f\u0645\u0627 \u064a\u0643\u0648\u0646 \u0646\u0634\u0627\u0637 PDE5 \u0639\u0627\u0644\u064a\u064b\u0627 \u0623\u0648 \u0639\u0646\u062f\u0645\u0627 \u062a\u0643\u0648\u0646 \u0627\u0644\u0625\u0634\u0627\u0631\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629\/\u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0636\u0639\u064a\u0641\u0629\u060c \u0642\u062f \u0644\u0627 \u064a\u0633\u062a\u0645\u0631 cGMP \u0628\u0645\u0627 \u064a\u0643\u0641\u064a \u0644\u062d\u062f\u0648\u062b \u0627\u0646\u062a\u0635\u0627\u0628 \u062c\u064a\u062f. \u0645\u062b\u0628\u0637\u0627\u062a PDE5<\/strong> \u062a\u0639\u0637\u0644 \u0647\u0630\u0627 \u0627\u0644\u0625\u0646\u0632\u064a\u0645 \u062c\u0632\u0626\u064a\u064b\u0627\u060c \u0641\u062a\u0633\u0645\u062d \u0644\u0640 cGMP \u0628\u0627\u0644\u0628\u0642\u0627\u0621 \u0645\u062f\u0629 \u0623\u0637\u0648\u0644\u060c \u0648\u0628\u0627\u0644\u062a\u0627\u0644\u064a \u064a\u062a\u062d\u0633\u0646 \u062a\u062f\u0641\u0642 \u0627\u0644\u062f\u0645 \u0648\u0627\u0633\u062a\u0645\u0631\u0627\u0631\u064a\u0629 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628.<\/p>\n

    \u0647\u0630\u0647 \u0627\u0644\u0646\u0642\u0637\u0629 \u062a\u0641\u0633\u0631 \u0634\u064a\u0626\u064b\u0627 \u064a\u0631\u0628\u0643 \u0627\u0644\u0646\u0627\u0633: \u0627\u0644\u062f\u0648\u0627\u0621 \u0644\u0627 \u064a\u0639\u0645\u0644 \u0641\u064a \u063a\u064a\u0627\u0628 \u0627\u0644\u0625\u062b\u0627\u0631\u0629. \u0644\u0623\u0646\u0647 \u0644\u0627 \u064a\u0637\u0644\u0642 \u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u0625\u0634\u0627\u0631\u0627\u062a \u0645\u0646 \u0627\u0644\u0628\u062f\u0627\u064a\u0629\u061b \u0628\u0644 \u064a\u062f\u0639\u0645\u0647\u0627. \u0644\u0630\u0644\u0643\u060c \u0625\u0630\u0627 \u0643\u0627\u0646 \u0627\u0644\u0633\u0628\u0628 \u0627\u0644\u0623\u0633\u0627\u0633\u064a \u0647\u0648 \u063a\u064a\u0627\u0628 \u0627\u0644\u0631\u063a\u0628\u0629\u060c \u0623\u0648 \u0623\u0644\u0645 \u0623\u062b\u0646\u0627\u0621 \u0627\u0644\u0639\u0644\u0627\u0642\u0629\u060c \u0623\u0648 \u0627\u0643\u062a\u0626\u0627\u0628 \u0634\u062f\u064a\u062f\u060c \u0623\u0648 \u062a\u0648\u062a\u0631 \u062e\u0627\u0646\u0642\u060c \u0641\u0642\u062f \u062a\u0643\u0648\u0646 \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0645\u062d\u062f\u0648\u062f\u0629 \u0645\u0647\u0645\u0627 \u0643\u0627\u0646 \u0627\u0644\u062f\u0648\u0627\u0621 \u201c\u0645\u0634\u0647\u0648\u0631\u064b\u0627\u201d.<\/p>\n

    \u0648\u062a\u0641\u0633\u0631 \u0623\u064a\u0636\u064b\u0627 \u0633\u0628\u0628 \u0627\u0644\u062a\u062f\u0627\u062e\u0644 \u0627\u0644\u062e\u0637\u064a\u0631 \u0645\u0639 \u0627\u0644\u0646\u062a\u0631\u0627\u062a: \u0643\u0644\u0627\u0647\u0645\u0627 \u064a\u0648\u0633\u0639 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0639\u0628\u0631 \u0645\u0633\u0627\u0631\u0627\u062a \u0645\u062a\u0642\u0627\u0631\u0628\u0629\u060c \u0648\u0627\u0644\u062c\u0645\u0639 \u0642\u062f \u064a\u0647\u0628\u0637 \u0627\u0644\u0636\u063a\u0637 \u0628\u0634\u0643\u0644 \u062d\u0627\u062f. \u0641\u064a \u0627\u0644\u0637\u0628\u060c \u0647\u0630\u0647 \u0644\u064a\u0633\u062a \u0646\u0638\u0631\u064a\u0629. \u0647\u0630\u0627 \u0633\u0628\u0628 \u0648\u0627\u0636\u062d \u0644\u0645\u0646\u0639 \u0627\u0644\u062c\u0645\u0639.<\/p>\n

    \u0627\u0644\u0631\u062d\u0644\u0629 \u0627\u0644\u062a\u0627\u0631\u064a\u062e\u064a\u0629: \u0645\u0646 \u0645\u062e\u062a\u0628\u0631\u0627\u062a \u0627\u0644\u0642\u0644\u0628 \u0625\u0644\u0649 \u0623\u0634\u0647\u0631 \u062f\u0648\u0627\u0621 \u062c\u0646\u0633\u064a<\/h2>\n

    6.1 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u0648\u0627\u0644\u062a\u0637\u0648\u064a\u0631<\/h3>\n

    \u0642\u0635\u0629 \u0633\u064a\u0644\u062f\u064a\u0646\u0627\u0641\u064a\u0644 \u062a\u064f\u0631\u0648\u0649 \u0643\u062b\u064a\u0631\u064b\u0627 \u0644\u0623\u0646\u0647\u0627 \u0645\u062b\u0627\u0644 \u0639\u0644\u0649 \u201c\u0625\u0639\u0627\u062f\u0629 \u062a\u0648\u0638\u064a\u0641\u201d \u062f\u0648\u0627\u0621. \u062a\u0645 \u062a\u0637\u0648\u064a\u0631\u0647 \u0641\u064a \u0627\u0644\u0623\u0635\u0644 \u0636\u0645\u0646 \u0623\u0628\u062d\u0627\u062b \u062a\u0633\u062a\u0647\u062f\u0641 \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 (\u062e\u0635\u0648\u0635\u064b\u0627 \u0627\u0644\u0630\u0628\u062d\u0629 \u0627\u0644\u0635\u062f\u0631\u064a\u0629). \u0623\u062b\u0646\u0627\u0621 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629\u060c \u0644\u0648\u062d\u0638 \u062a\u0623\u062b\u064a\u0631 \u062c\u0627\u0646\u0628\u064a \u0644\u0627\u0641\u062a \u064a\u062a\u0639\u0644\u0642 \u0628\u062a\u062d\u0633\u0646 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628. \u0647\u0646\u0627 \u062a\u063a\u064a\u0651\u0631 \u0645\u0633\u0627\u0631 \u0627\u0644\u062a\u0637\u0648\u064a\u0631 \u0628\u0627\u0644\u0643\u0627\u0645\u0644 \u062a\u0642\u0631\u064a\u0628\u064b\u0627. \u0643\u0635\u062d\u0641\u064a \u0637\u0628\u064a\u060c \u0623\u062d\u0628 \u0647\u0630\u0647 \u0627\u0644\u0642\u0635\u0635 \u0644\u0623\u0646\u0647\u0627 \u062a\u0630\u0643\u0651\u0631\u0646\u0627 \u0623\u0646 \u0627\u0644\u0639\u0644\u0645 \u0644\u0627 \u064a\u0633\u064a\u0631 \u0628\u062e\u0637 \u0645\u0633\u062a\u0642\u064a\u0645\u060c \u0648\u0623\u0646 \u0627\u0644\u0645\u0644\u0627\u062d\u0638\u0629 \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0642\u062f \u062a\u0641\u062a\u062d \u0628\u0627\u0628\u064b\u0627 \u0639\u0644\u0627\u062c\u064a\u064b\u0627 \u062c\u062f\u064a\u062f\u064b\u0627.<\/p>\n

    \u0628\u0639\u062f \u0646\u062c\u0627\u062d \u0633\u064a\u0644\u062f\u064a\u0646\u0627\u0641\u064a\u0644\u060c \u0638\u0647\u0631\u062a \u0623\u062f\u0648\u064a\u0629 \u0623\u062e\u0631\u0649 \u0645\u0646 \u0646\u0641\u0633 \u0627\u0644\u0641\u0626\u0629 \u0628\u062e\u0635\u0627\u0626\u0635 \u0645\u062e\u062a\u0644\u0641\u0629\u060c \u0645\u062b\u0644 \u062a\u0627\u062f\u0627\u0644\u0627\u0641\u064a\u0644 \u0627\u0644\u0630\u064a \u062a\u0645\u064a\u0632 \u0628\u0645\u062f\u0629 \u0623\u0637\u0648\u0644\u060c \u0648\u0641\u0627\u0631\u062f\u064a\u0646\u0627\u0641\u064a\u0644\u060c \u062b\u0645 \u0623\u0641\u0627\u0646\u0627\u0641\u064a\u0644. \u0627\u0644\u0645\u0646\u0627\u0641\u0633\u0629 \u0647\u0646\u0627 \u0644\u0645 \u062a\u0643\u0646 \u0641\u0642\u0637 \u0639\u0644\u0649 \u201c\u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629\u201d\u060c \u0628\u0644 \u0639\u0644\u0649 \u0646\u0645\u0637 \u0627\u0644\u062d\u064a\u0627\u0629: \u0646\u0627\u0641\u0630\u0629 \u0632\u0645\u0646\u064a\u0629 \u0623\u0637\u0648\u0644\u060c \u0623\u0648 \u0628\u062f\u0621 \u0623\u0633\u0631\u0639\u060c \u0623\u0648 \u0622\u062b\u0627\u0631 \u062c\u0627\u0646\u0628\u064a\u0629 \u0623\u0642\u0644 \u0644\u062f\u0649 \u0628\u0639\u0636 \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u064a\u0646.<\/p>\n

    6.2 \u0645\u062d\u0637\u0627\u062a \u062a\u0646\u0638\u064a\u0645\u064a\u0629 (Regulatory milestones)<\/h3>\n

    \u0627\u0639\u062a\u0645\u0627\u062f \u0623\u0648\u0644 \u0645\u062b\u0628\u0637 PDE5 \u0644\u0639\u0644\u0627\u062c \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0643\u0627\u0646 \u0646\u0642\u0637\u0629 \u062a\u062d\u0648\u0644 \u0641\u064a \u0627\u0644\u0637\u0628 \u0627\u0644\u0639\u0627\u0645\u060c \u0644\u0623\u0646\u0647 \u0646\u0642\u0644 \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0645\u0646 \u0647\u0627\u0645\u0634 \u0627\u0644\u062d\u062f\u064a\u062b \u0625\u0644\u0649 \u0642\u0644\u0628 \u0627\u0644\u0639\u064a\u0627\u062f\u0629. \u0644\u0645 \u064a\u0639\u062f \u0627\u0644\u0645\u0648\u0636\u0648\u0639 \u0645\u062c\u0631\u062f \u201c\u0646\u0635\u064a\u062d\u0629\u201d \u0623\u0648 \u201c\u0648\u0635\u0641\u0629 \u0634\u0639\u0628\u064a\u0629\u201d\u060c \u0628\u0644 \u0623\u0635\u0628\u062d \u0644\u0647 \u0639\u0644\u0627\u062c \u062f\u0648\u0627\u0626\u064a \u0645\u062f\u0631\u0648\u0633\u060c \u0648\u062a\u062d\u0630\u064a\u0631\u0627\u062a \u0648\u0627\u0636\u062d\u0629\u060c \u0648\u0645\u0639\u0627\u064a\u064a\u0631 \u0645\u062a\u0627\u0628\u0639\u0629. \u0647\u0630\u0627 \u0627\u0644\u0627\u0639\u062a\u0645\u0627\u062f \u062f\u0641\u0639 \u0623\u064a\u0636\u064b\u0627 \u0625\u0644\u0649 \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0623\u0628\u062d\u0627\u062b \u062d\u0648\u0644 \u0635\u062d\u0629 \u0627\u0644\u0631\u062c\u0644\u060c \u0648\u0627\u0644\u0633\u0643\u0631\u064a\u060c \u0648\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0643\u0639\u0648\u0627\u0645\u0644 \u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628.<\/p>\n

    \u0644\u0627\u062d\u0642\u064b\u0627\u060c \u062a\u0648\u0633\u0639\u062a \u0627\u0644\u0627\u0639\u062a\u0645\u0627\u062f\u0627\u062a \u0644\u0628\u0639\u0636 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0627\u062a \u0623\u062e\u0631\u0649 \u0645\u062b\u0644 \u062a\u0636\u062e\u0645 \u0627\u0644\u0628\u0631\u0648\u0633\u062a\u0627\u062a\u0627 \u0627\u0644\u062d\u0645\u064a\u062f (\u0644\u062a\u0627\u062f\u0627\u0644\u0627\u0641\u064a\u0644) \u0648\u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u0634\u0631\u064a\u0627\u0646 \u0627\u0644\u0631\u0626\u0648\u064a (\u0644\u0633\u064a\u0644\u062f\u064a\u0646\u0627\u0641\u064a\u0644 \u0628\u062a\u062d\u0636\u064a\u0631 \u0645\u062e\u062a\u0644\u0641). \u0647\u0630\u0647 \u0627\u0644\u062a\u0648\u0633\u0639\u0627\u062a \u0644\u0645 \u062a\u0623\u062a\u0650 \u0645\u0646 \u0641\u0631\u0627\u063a\u061b \u062c\u0627\u0621\u062a \u0645\u0646 \u062f\u0631\u0627\u0633\u0627\u062a \u0648\u062a\u062c\u0627\u0631\u0628 \u0648\u0645\u0631\u0627\u062c\u0639\u0627\u062a \u062a\u0646\u0638\u064a\u0645\u064a\u0629.<\/p>\n

    6.3 \u062a\u0637\u0648\u0631 \u0627\u0644\u0633\u0648\u0642 \u0648\u0627\u0644\u062c\u0646\u064a\u0633 (Generics)<\/h3>\n

    \u0645\u0639 \u0627\u0646\u062a\u0647\u0627\u0621 \u0641\u062a\u0631\u0627\u062a \u0627\u0644\u062d\u0645\u0627\u064a\u0629 \u0644\u0628\u0639\u0636 \u0627\u0644\u0639\u0644\u0627\u0645\u0627\u062a \u0627\u0644\u062a\u062c\u0627\u0631\u064a\u0629\u060c \u0627\u0646\u062a\u0634\u0631\u062a \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062c\u0646\u064a\u0633\u0629 \u0639\u0644\u0649 \u0646\u0637\u0627\u0642 \u0648\u0627\u0633\u0639. \u0647\u0630\u0627 \u063a\u064a\u0651\u0631 \u0627\u0644\u0648\u0635\u0648\u0644 \u0648\u0627\u0644\u062a\u0643\u0644\u0641\u0629 \u0641\u064a \u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u0628\u0644\u062f\u0627\u0646\u060c \u0644\u0643\u0646\u0647 \u062e\u0644\u0642 \u062a\u062d\u062f\u064a\u064b\u0627 \u0622\u062e\u0631: \u0627\u0644\u062a\u0645\u064a\u064a\u0632 \u0628\u064a\u0646 \u062c\u0646\u064a\u0633 \u0645\u0648\u062b\u0648\u0642 \u0645\u0646 \u0634\u0631\u0643\u0629 \u0645\u0644\u062a\u0632\u0645\u0629 \u0628\u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u062a\u0635\u0646\u064a\u0639\u060c \u0648\u0628\u064a\u0646 \u0645\u0646\u062a\u062c\u0627\u062a \u0645\u062c\u0647\u0648\u0644\u0629 \u0627\u0644\u0645\u0635\u062f\u0631 \u062a\u064f\u0628\u0627\u0639 \u0639\u0628\u0631 \u0627\u0644\u0625\u0646\u062a\u0631\u0646\u062a. \u0623\u062d\u064a\u0627\u0646\u064b\u0627 \u064a\u0638\u0646 \u0627\u0644\u0646\u0627\u0633 \u0623\u0646 \u201c\u0627\u0644\u062c\u0646\u064a\u0633\u201d \u064a\u0639\u0646\u064a \u201c\u0631\u062f\u064a\u0621\u201d. \u0647\u0630\u0627 \u063a\u064a\u0631 \u0635\u062d\u064a\u062d \u0628\u0627\u0644\u0636\u0631\u0648\u0631\u0629. \u0627\u0644\u062c\u0646\u064a\u0633 \u0627\u0644\u062f\u0648\u0627\u0626\u064a \u0627\u0644\u0645\u0639\u062a\u0645\u062f \u064a\u0641\u062a\u0631\u0636 \u0623\u0646 \u064a\u0637\u0627\u0628\u0642 \u0627\u0644\u0645\u0627\u062f\u0629 \u0627\u0644\u0641\u0639\u0627\u0644\u0629 \u0648\u0627\u0644\u062c\u0648\u062f\u0629 \u0636\u0645\u0646 \u0645\u0639\u0627\u064a\u064a\u0631 \u0645\u062d\u062f\u062f\u0629\u060c \u0644\u0643\u0646 \u0627\u0644\u0645\u0634\u0643\u0644\u0629 \u062a\u0638\u0647\u0631 \u0639\u0646\u062f\u0645\u0627 \u064a\u0643\u0648\u0646 \u0627\u0644\u0645\u0646\u062a\u062c \u062e\u0627\u0631\u062c \u0627\u0644\u0642\u0646\u0648\u0627\u062a \u0627\u0644\u0646\u0638\u0627\u0645\u064a\u0629.<\/p>\n

    \u0627\u0644\u0645\u062c\u062a\u0645\u0639\u060c \u0627\u0644\u0648\u0635\u0648\u0644\u060c \u0648\u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0648\u0627\u0642\u0639\u064a: \u0645\u0627 \u0627\u0644\u0630\u064a \u064a\u062d\u062f\u062b \u062e\u0627\u0631\u062c \u0627\u0644\u0643\u062a\u0628\u061f<\/h2>\n

    \u0627\u0644\u062d\u062f\u064a\u062b \u0639\u0646 \u0623\u0641\u0636\u0644 \u062d\u0628\u0648\u0628 \u0644\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0644\u0627 \u064a\u0643\u062a\u0645\u0644 \u062f\u0648\u0646 \u0627\u0644\u0627\u0639\u062a\u0631\u0627\u0641 \u0628\u0627\u0644\u0648\u0627\u0642\u0639 \u0627\u0644\u0627\u062c\u062a\u0645\u0627\u0639\u064a. \u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u0631\u062c\u0627\u0644 \u064a\u062a\u0623\u062e\u0631\u0648\u0646 \u0641\u064a \u0637\u0644\u0628 \u0627\u0644\u0645\u0633\u0627\u0639\u062f\u0629. \u0627\u0644\u0633\u0628\u0628 \u0644\u064a\u0633 \u062f\u0627\u0626\u0645\u064b\u0627 \u0627\u0644\u062c\u0647\u0644\u061b \u0623\u062d\u064a\u0627\u0646\u064b\u0627 \u0647\u0648 \u0627\u0644\u062e\u062c\u0644\u060c \u0623\u0648 \u0627\u0644\u062e\u0648\u0641 \u0645\u0646 \u0627\u0644\u062d\u0643\u0645\u060c \u0623\u0648 \u0627\u0644\u0627\u0639\u062a\u0642\u0627\u062f \u0623\u0646 \u0627\u0644\u0645\u0634\u0643\u0644\u0629 \u201c\u0646\u0647\u0627\u064a\u0629 \u0627\u0644\u0631\u062c\u0648\u0644\u0629\u201d. \u0639\u0644\u0649 \u0623\u0631\u0636 \u0627\u0644\u0648\u0627\u0642\u0639\u060c \u0636\u0639\u0641 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0628 \u0639\u0631\u0636 \u0637\u0628\u064a \u0634\u0627\u0626\u0639\u060c \u0648\u0642\u062f \u064a\u0643\u0648\u0646 \u0623\u0648\u0644 \u062e\u064a\u0637 \u064a\u0642\u0648\u062f \u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u0633\u0643\u0631\u064a \u0623\u0648 \u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0623\u0648 \u0627\u0636\u0637\u0631\u0627\u0628 \u062f\u0647\u0648\u0646.<\/p>\n

    7.1 \u0627\u0644\u0648\u0639\u064a \u0627\u0644\u0639\u0627\u0645 \u0648\u0627\u0644\u0648\u0635\u0645\u0629<\/h3>\n

    \u0645\u0646 \u0627\u0644\u0623\u0634\u064a\u0627\u0621 \u0627\u0644\u062a\u064a \u0623\u0644\u0627\u062d\u0638\u0647\u0627 \u064a\u0648\u0645\u064a\u064b\u0627 \u0641\u064a \u0627\u0644\u0631\u0633\u0627\u0626\u0644 \u0648\u0627\u0644\u062a\u0639\u0644\u064a\u0642\u0627\u062a: \u0627\u0644\u0646\u0627\u0633 \u062a\u0631\u064a\u062f \u0625\u062c\u0627\u0628\u0629 \u0633\u0631\u064a\u0639\u0629 \u062f\u0648\u0646 \u0643\u0634\u0641 \u062a\u0641\u0627\u0635\u064a\u0644. \u0645\u0641\u0647\u0648\u0645. \u0644\u0643\u0646 \u0627\u0644\u0637\u0628 \u064a\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0627\u0644\u062a\u0641\u0627\u0635\u064a\u0644. \u0647\u0644 \u0627\u0644\u0645\u0634\u0643\u0644\u0629 \u0645\u0641\u0627\u062c\u0626\u0629 \u0623\u0645 \u062a\u062f\u0631\u064a\u062c\u064a\u0629\u061f \u0647\u0644 \u062a\u0648\u062c\u062f \u0627\u0646\u062a\u0635\u0627\u0628\u0627\u062a \u0635\u0628\u0627\u062d\u064a\u0629\u061f \u0647\u0644 \u0647\u0646\u0627\u0643 \u0623\u0644\u0645\u061f \u0647\u0644 \u062a\u0648\u062c\u062f \u0623\u062f\u0648\u064a\u0629 \u062c\u062f\u064a\u062f\u0629\u061f \u0647\u0630\u0647 \u0627\u0644\u0623\u0633\u0626\u0644\u0629 \u0644\u064a\u0633\u062a \u0641\u0636\u0648\u0644\u064b\u0627\u061b \u0647\u064a \u0645\u0641\u0627\u062a\u064a\u062d \u062a\u0634\u062e\u064a\u0635.<\/p>\n

    \u0627\u0644\u0648\u0635\u0645\u0629 \u062a\u062a\u0631\u0627\u062c\u0639 \u0628\u0628\u0637\u0621\u060c \u0644\u0643\u0646 \u0645\u0627 \u0632\u0627\u0644\u062a \u0645\u0648\u062c\u0648\u062f\u0629. \u0623\u062d\u064a\u0627\u0646\u064b\u0627 \u0623\u0633\u0645\u0639 \u062c\u0645\u0644\u0629: \u201c\u0644\u0627 \u0623\u0631\u064a\u062f \u0623\u0646 \u064a\u0639\u0631\u0641 \u0623\u062d\u062f.\u201d \u0628\u064a\u0646\u0645\u0627 \u0627\u0644\u062d\u0642\u064a\u0642\u0629 \u0623\u0646 \u0627\u0644\u0637\u0628\u064a\u0628 \u0633\u0645\u0639 \u0647\u0630\u0627 \u0622\u0644\u0627\u0641 \u0627\u0644\u0645\u0631\u0627\u062a. \u0644\u0627 \u062c\u062f\u064a\u062f. \u0645\u0627 \u064a\u0647\u0645 \u0647\u0648 \u0623\u0646 \u0644\u0627 \u064a\u062a\u062d\u0648\u0644 \u0627\u0644\u062e\u062c\u0644 \u0625\u0644\u0649 \u0634\u0631\u0627\u0621 \u0639\u0634\u0648\u0627\u0626\u064a \u0645\u0646 \u0627\u0644\u0625\u0646\u062a\u0631\u0646\u062a.<\/p>\n

    7.2 \u0627\u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0627\u0644\u0645\u0642\u0644\u062f\u0629 \u0648\u0645\u062e\u0627\u0637\u0631 \u201c\u0635\u064a\u062f\u0644\u064a\u0627\u062a \u0627\u0644\u0625\u0646\u062a\u0631\u0646\u062a\u201d<\/h3>\n

    \u0647\u0630\u0647 \u0646\u0642\u0637\u0629 \u0644\u0627 \u0623\u062d\u0628 \u062a\u0644\u0637\u064a\u0641\u0647\u0627: \u0633\u0648\u0642 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062c\u0646\u0633\u064a\u0629 \u0645\u0646 \u0623\u0643\u062b\u0631 \u0627\u0644\u0623\u0633\u0648\u0627\u0642 \u062a\u0639\u0631\u0636\u064b\u0627 \u0644\u0644\u062a\u0632\u0648\u064a\u0631. \u0627\u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0627\u0644\u0645\u0642\u0644\u062f\u0629 \u0642\u062f \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u062c\u0631\u0639\u0627\u062a \u062e\u0627\u0637\u0626\u0629\u060c \u0623\u0648 \u0645\u0648\u0627\u062f \u063a\u064a\u0631 \u0645\u0639\u0644\u0646\u0629\u060c \u0623\u0648 \u0645\u0644\u0648\u062b\u0627\u062a. \u0627\u0644\u062e\u0637\u0631 \u0644\u064a\u0633 \u0641\u0642\u0637 \u201c\u0639\u062f\u0645 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629\u201d\u060c \u0628\u0644 \u062d\u062f\u0648\u062b \u0647\u0628\u0648\u0637 \u0636\u063a\u0637\u060c \u0623\u0648 \u062a\u062f\u0627\u062e\u0644\u0627\u062a \u062e\u0637\u064a\u0631\u0629\u060c \u0623\u0648 \u0623\u0639\u0631\u0627\u0636 \u063a\u064a\u0631 \u0645\u062a\u0648\u0642\u0639\u0629. \u0627\u0644\u0645\u0631\u0636\u0649 \u064a\u062e\u0628\u0631\u0648\u0646\u0646\u064a \u0623\u062d\u064a\u0627\u0646\u064b\u0627: \u201c\u0627\u0634\u062a\u0631\u064a\u062a\u0647\u0627 \u0648\u0643\u0627\u0646\u062a \u0631\u062e\u064a\u0635\u0629 \u062c\u062f\u064b\u0627.\u201d \u0648\u0623\u0646\u0627 \u0623\u0641\u0643\u0631: \u0627\u0644\u0631\u062e\u0635 \u0647\u0646\u0627 \u0644\u064a\u0633 \u0645\u064a\u0632\u0629\u060c \u0628\u0644 \u0639\u0644\u0627\u0645\u0629 \u0627\u0633\u062a\u0641\u0647\u0627\u0645.<\/p>\n

    \u0625\u0630\u0627 \u0643\u0627\u0646 \u0627\u0644\u0634\u062e\u0635 \u064a\u0641\u0643\u0631 \u0641\u064a \u0627\u0644\u0639\u0644\u0627\u062c\u060c \u0641\u0627\u0644\u0623\u0643\u062b\u0631 \u0623\u0645\u0627\u0646\u064b\u0627 \u0647\u0648 \u0627\u0644\u0645\u0631\u0648\u0631 \u0639\u0628\u0631 \u0642\u0646\u0627\u0629 \u0635\u062d\u064a\u0629 \u0646\u0638\u0627\u0645\u064a\u0629: \u0637\u0628\u064a\u0628\u060c \u0635\u064a\u062f\u0644\u064a\u060c \u0623\u0648 \u0646\u0638\u0627\u0645 \u0648\u0635\u0641\u0627\u062a \u0645\u0639\u062a\u0645\u062f \u062d\u0633\u0628 \u0642\u0648\u0627\u0646\u064a\u0646 \u0627\u0644\u0628\u0644\u062f. \u0627\u0644\u0642\u0648\u0627\u0646\u064a\u0646 \u062a\u062e\u062a\u0644\u0641\u060c \u0648\u0628\u0639\u0636 \u0627\u0644\u062f\u0648\u0644 \u0644\u062f\u064a\u0647\u0627 \u0646\u0645\u0627\u0630\u062c \u0635\u0631\u0641 \u0645\u062e\u062a\u0644\u0641\u0629 (\u0648\u0635\u0641\u0629\u060c \u0623\u0648 \u0635\u0631\u0641 \u0645\u0642\u064a\u062f\u060c \u0623\u0648 \u0625\u0634\u0631\u0627\u0641 \u0635\u064a\u062f\u0644\u064a). \u0644\u0627 \u062a\u0648\u062c\u062f \u0642\u0627\u0639\u062f\u0629 \u0648\u0627\u062d\u062f\u0629 \u0639\u0627\u0644\u0645\u064a\u0629.<\/p>\n

    7.3 \u0627\u0644\u062c\u0646\u064a\u0633 \u0645\u0642\u0627\u0628\u0644 \u0627\u0644\u0639\u0644\u0627\u0645\u0629 \u0627\u0644\u062a\u062c\u0627\u0631\u064a\u0629: \u0645\u0627\u0630\u0627 \u064a\u0639\u0646\u064a \u0630\u0644\u0643 \u0644\u0644\u0645\u0631\u064a\u0636\u061f<\/h3>\n

    \u0645\u0646 \u0627\u0644\u0646\u0627\u062d\u064a\u0629 \u0627\u0644\u0639\u0644\u0645\u064a\u0629\u060c \u0627\u0644\u062c\u0646\u064a\u0633 \u0627\u0644\u0645\u0639\u062a\u0645\u062f \u064a\u064f\u0641\u062a\u0631\u0636 \u0623\u0646 \u064a\u0642\u062f\u0645 \u0646\u0641\u0633 \u0627\u0644\u0645\u0627\u062f\u0629 \u0627\u0644\u0641\u0639\u0627\u0644\u0629 \u0648\u0628\u062c\u0648\u062f\u0629 \u0645\u0643\u0627\u0641\u0626\u0629 \u0636\u0645\u0646 \u0645\u0639\u0627\u064a\u064a\u0631 \u0645\u062d\u062f\u062f\u0629. \u0644\u0643\u0646 \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0627\u0644\u0648\u0627\u0642\u0639\u064a\u0629 \u0642\u062f \u062a\u062e\u062a\u0644\u0641 \u0628\u0633\u0628\u0628 \u0639\u0648\u0627\u0645\u0644 \u0645\u062b\u0644 \u0627\u0644\u0633\u0648\u0627\u063a\u0627\u062a (excipients) \u0623\u0648 \u0627\u062e\u062a\u0644\u0627\u0641\u0627\u062a \u0637\u0641\u064a\u0641\u0629 \u0641\u064a \u0627\u0644\u0627\u0645\u062a\u0635\u0627\u0635 \u0636\u0645\u0646 \u0627\u0644\u062d\u062f\u0648\u062f \u0627\u0644\u0645\u0642\u0628\u0648\u0644\u0629. \u0625\u0630\u0627 \u0627\u0634\u062a\u0643\u0649 \u0634\u062e\u0635 \u0645\u0646 \u0627\u062e\u062a\u0644\u0627\u0641 \u0648\u0627\u0636\u062d \u0628\u0639\u062f \u062a\u063a\u064a\u064a\u0631 \u0627\u0644\u0634\u0631\u0643\u0629\u060c \u0644\u0627 \u0623\u0633\u062e\u0631 \u0645\u0646 \u0630\u0644\u0643. \u0623\u0631\u0627\u062c\u0639 \u0645\u0639\u0647 \u0627\u0644\u0645\u0635\u062f\u0631\u060c \u0648\u0623\u062a\u0623\u0643\u062f \u0645\u0646 \u0627\u0644\u0627\u0639\u062a\u0645\u0627\u062f\u060c \u0648\u0623\u0628\u062d\u062b \u0639\u0646 \u062a\u0641\u0633\u064a\u0631 \u0645\u0646\u0637\u0642\u064a.<\/p>\n

    \u0627\u0644\u0645\u0647\u0645: \u0644\u0627 \u062a\u062c\u0639\u0644 \u201c\u0627\u0644\u0627\u0633\u0645\u201d \u0647\u0648 \u0645\u0639\u064a\u0627\u0631\u0643 \u0627\u0644\u0648\u062d\u064a\u062f. \u0645\u0639\u064a\u0627\u0631\u0643 \u0627\u0644\u062d\u0642\u064a\u0642\u064a \u0647\u0648 \u0627\u0644\u0633\u0644\u0627\u0645\u0629\u060c \u0648\u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u0635\u062d\u064a\u062d\u060c \u0648\u0645\u0631\u0627\u062c\u0639\u0629 \u0627\u0644\u062a\u062f\u0627\u062e\u0644\u0627\u062a. \u0625\u0630\u0627 \u0643\u0627\u0646 \u0644\u062f\u064a\u0643 \u0623\u0645\u0631\u0627\u0636 \u0645\u0632\u0645\u0646\u0629 \u0623\u0648 \u062a\u062a\u0646\u0627\u0648\u0644 \u0623\u062f\u0648\u064a\u0629 \u0645\u062a\u0639\u062f\u062f\u0629\u060c \u0641\u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u0627\u0644\u0645\u0647\u0646\u064a\u0629 \u0644\u064a\u0633\u062a \u0631\u0641\u0627\u0647\u064a\u0629.<\/p>\n

    7.4 \u0646\u0645\u0627\u0630\u062c \u0627\u0644\u0648\u0635\u0648\u0644 \u0627\u0644\u0625\u0642\u0644\u064a\u0645\u064a: \u0648\u0635\u0641\u0629 \u0623\u0645 \u0628\u062f\u0648\u0646 \u0648\u0635\u0641\u0629\u061f<\/h3>\n

    \u064a\u064f\u0641\u0627\u062c\u0623 \u0643\u062b\u064a\u0631\u0648\u0646 \u0639\u0646\u062f\u0645\u0627 \u064a\u0639\u0644\u0645\u0648\u0646 \u0623\u0646 \u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0648\u0635\u0648\u0644 \u062a\u062e\u062a\u0644\u0641 \u062c\u0630\u0631\u064a\u064b\u0627 \u0628\u064a\u0646 \u0627\u0644\u0628\u0644\u062f\u0627\u0646. \u0641\u064a \u0623\u0645\u0627\u0643\u0646 \u062a\u064f\u0635\u0631\u0641 \u0641\u0642\u0637 \u0628\u0648\u0635\u0641\u0629\u060c \u0648\u0641\u064a \u0623\u0645\u0627\u0643\u0646 \u0642\u062f \u062a\u0648\u062c\u062f \u0646\u0645\u0627\u0630\u062c \u0635\u0631\u0641 \u0628\u0625\u0634\u0631\u0627\u0641 \u0635\u064a\u062f\u0644\u064a\u060c \u0648\u0641\u064a \u0623\u0645\u0627\u0643\u0646 \u0623\u062e\u0631\u0649 \u062a\u0646\u062a\u0634\u0631 \u0627\u0644\u0633\u0648\u0642 \u0627\u0644\u0631\u0645\u0627\u062f\u064a\u0629. \u0647\u0630\u0627 \u0627\u0644\u062a\u0641\u0627\u0648\u062a \u064a\u062e\u0644\u0642 \u0627\u0631\u062a\u0628\u0627\u0643\u064b\u0627: \u0634\u062e\u0635 \u064a\u0633\u0627\u0641\u0631 \u0641\u064a\u0634\u062a\u0631\u064a \u0645\u0646 \u0628\u0644\u062f \u0645\u0627 \u062b\u0645 \u064a\u0633\u062a\u062e\u062f\u0645\u0647 \u0641\u064a \u0628\u0644\u062f \u0622\u062e\u0631 \u062f\u0648\u0646 \u0645\u062a\u0627\u0628\u0639\u0629. \u0647\u0646\u0627 \u062a\u0638\u0647\u0631 \u0645\u0634\u0643\u0644\u0627\u062a \u0645\u062b\u0644 \u0627\u062e\u062a\u0644\u0627\u0641 \u0627\u0644\u062a\u0631\u0643\u064a\u0632\u0627\u062a \u0623\u0648 \u0627\u0644\u062a\u062d\u0636\u064a\u0631\u0627\u062a \u0623\u0648 \u062d\u062a\u0649 \u0627\u062e\u062a\u0644\u0627\u0641 \u062c\u0648\u062f\u0629 \u0627\u0644\u0645\u0646\u062a\u062c.<\/p>\n

    \u0625\u0630\u0627 \u0623\u0631\u062f\u062a \u0646\u0642\u0637\u0629 \u0639\u0645\u0644\u064a\u0629 \u0648\u0627\u062d\u062f\u0629: \u0642\u0628\u0644 \u0627\u0644\u062a\u0641\u0643\u064a\u0631 \u0641\u064a \u0623\u064a \u062f\u0648\u0627\u0621 \u0644\u0644\u0627\u0646\u062a\u0635\u0627\u0628\u060c \u0627\u062c\u0645\u0639 \u0642\u0627\u0626\u0645\u0629 \u0623\u062f\u0648\u064a\u062a\u0643 \u0627\u0644\u062d\u0627\u0644\u064a\u0629 \u0648\u0623\u0645\u0631\u0627\u0636\u0643 \u0627\u0644\u0645\u0632\u0645\u0646\u0629\u060c \u0648\u0646\u0627\u0642\u0634\u0647\u0627 \u0645\u0639 \u0645\u062e\u062a\u0635. \u0647\u0630\u0647 \u0627\u0644\u062e\u0637\u0648\u0629 \u0648\u062d\u062f\u0647\u0627 \u062a\u0645\u0646\u0639 \u0623\u062e\u0637\u0627\u0621 \u0643\u062b\u064a\u0631\u0629.<\/p>\n

    \u062e\u0644\u0627\u0635\u0629: \u0645\u0627 \u0627\u0644\u0630\u064a \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0642\u062f\u0645\u0647 \u201c\u0623\u0641\u0636\u0644 \u062d\u0628\u0648\u0628 \u0644\u0644\u0627\u0646\u062a\u0635\u0627\u0628\u201d \u0648\u0645\u0627 \u0627\u0644\u0630\u064a \u0644\u0627 \u062a\u0633\u062a\u0637\u064a\u0639 \u062a\u0642\u062f\u064a\u0645\u0647\u061f<\/h2>\n

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